Evidence map›Paper›PMID 39858453›Full record

ArticleBiomolecules2025

Characterization of the Sodium Multi-Vitamin Transporter in the Mosquito

Jun Isoe, Brendan F Riske, Megan E Dobson, Hannah L Kaylor, Jessica C Brady, Yared Debebe, Laura M Saavedra, Shirley Luckhart, Michael A Riehle

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Pathogens (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jun IsoeDepartment of Entomology, University of Arizona, Tucson, AZ 85721, USA.
Brendan F RiskeDepartment of Entomology, University of Arizona, Tucson, AZ 85721, USA.
Megan E DobsonDepartment of Biological Sciences, University of Idaho, Moscow, ID 83844, USA.
Hannah L KaylorDepartment of Entomology, Plant Pathology and Nematology, University of Idaho, Moscow, ID 83844, USA.
Jessica C BradyDepartment of Biological Sciences, University of Idaho, Moscow, ID 83844, USA.
Yared DebebeDepartment of Entomology, Plant Pathology and Nematology, University of Idaho, Moscow, ID 83844, USA.
Laura M SaavedraDepartment of Entomology, University of Arizona, Tucson, AZ 85721, USA.
Shirley LuckhartDepartment of Biological Sciences, University of Idaho, Moscow, ID 83844, USA.ORCID 0000-0001-5047-4683
Michael A RiehleDepartment of Entomology, University of Arizona, Tucson, AZ 85721, USA.ORCID 0000-0001-9747-3872

Funding

How to starve a parasite: Manipulating CoA biosynthesis to control Plasmodium development in the mosquitoR01AI170506 · NIAID · UNIVERSITY OF ARIZONA · PI Shirley Luckhart, Michael Allen Riehle · 2023 to 2026
$2.5M
Bridges to the Baccalaureate Research Training Program T34T34GM142620 · NIGMS · UNIVERSITY OF IDAHO · PI Brandy Fries, Kristopher V Waynant · 2023 to 2026
$710k
NIAID NIH HHS R01 AI170506NIGMS NIH HHS T34 GM142620NIH HHS 1R01AI170506-02A1NIH HHS 1T34GM142620-01A1
6 · The paper itself

Abstract

Pantothenate (Pan), or vitamin B5, is essential for the synthesis of co-enzyme A (CoA), acetyl-CoA, and numerous downstream physiological processes. We previously demonstrated that Pan is not only essential for mosquito survival, but also for the development of malaria parasites within the mosquito, suggesting that targeting Pan and CoA biosynthesis may be a novel approach for malaria control. However, little is known about how Pan is acquired and mobilized within the mosquito. In this work, we examined Pan levels in the important human malaria vector

Indexed as

AnophelesBiotinInsect ProteinsPantothenic AcidAnimalsMosquito VectorsBiotinInsect ProteinsPantothenic AcidAnopheles stephensibiotinmalariamosquitopantothenatereproductionSMVTsurvivaltransportvitamin B5vitamin B7

Identifiers

PMID39858453
PMCPMC11764013

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.