Evidence map›Paper›PMID 39858607›Full record

ArticleGenes2025

Novel

Yasuhiro Arai, Shin-Ya Nishio, Shinichi Goto, Yumiko Kobayashi, Yohei Honkura, Akira Ganaha, Kotaro Ishikawa, Shin-Ichiro Oka, Hiroshi Futagawa, Mayuri Okami and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Yasuhiro AraiDepartment of Otorhinolaryngology-Head and Neck Surgery, Yokohama City University School of Medicine, Yokohama 236-0004, Japan.
Shin-Ya NishioDepartment of Hearing Implant Sciences, Shinshu University School of Medicine, Matsumoto 390-8621, Japan.ORCID 0000-0001-6640-2297
Shinichi GotoDepartment of Otorhinolaryngology Head and Neck Surgery, Hirosaki University School of Medicine, Hirosaki 036-8562, Japan.
Yumiko KobayashiDepartment of Otorhinolaryngology and Head and Neck Surgery, Iwate Medical University, Morioka 028-3694, Japan.
Yohei HonkuraDepartment of Otolaryngology-Head and Neck Surgery, Tohoku University School of Medicine, Sendai 980-8575, Japan.
Akira GanahaDepartment of Otorhinolaryngology, International University of Health and Welfare, Narita Hospital, Narita 286-0124, Japan.ORCID 0000-0002-2800-8886
Kotaro IshikawaDepartment of Otolaryngology, National Rehabilitation Center for Persons with Disabilities, Tokorozawa 359-8555, Japan.
Shin-Ichiro OkaDepartment of Otorhinolaryngology, International University of Health and Welfare, Mita Hospital, Tokyo 108-8329, Japan.
Hiroshi FutagawaDepartment of Medical Genetics, Tokyo Metropolitan Children's Medical Center, Tokyo 183-8561, Japan.ORCID 0000-0001-8939-4648
Mayuri OkamiDepartment of Otorhinolaryngology, Tokai University School of Medicine, Isehara 259-1193, Japan.
Fumio TakadaDepartment of Medical Genetics and Genomics, Kitasato University Graduate School of Medical Sciences, Sagamihara 252-0373, Japan.ORCID 0000-0003-4038-4275
Kyoko NagaiTAKASAKI Ear Nose and Throat Clinic, Takasaki 370-0031, Japan.
Tomoko EsakiDepartment of Otolaryngology, Aichi Children's Health and Medical Center, Obu 474-8710, Japan.
Takayuki OkanoDepartment of Otolaryngology, Fujita Health University Bantane Hospital, Nagoya 454-8509, Japan.
Yumi OhtaDepartment of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, Suita 565-0871, Japan.
Shin MasudaDepartment of Pediatric Rehabilitation, Hiroshima Prefectural Hospital, Hiroshima 734-8530, Japan.
Kentaro EgusaDepartment of Otorhinolaryngology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima 730-8518, Japan.
Masato TeraokaDepartment of Otolaryngology, Head and Neck Surgery, Ehime University Graduate School of Medicine, Toon 791-0295, Japan.
Kazuma SugaharaDepartment of Otolaryngology, Yamaguchi University Graduate School of Medicine, Ube 755-8505, Japan.ORCID 0000-0003-0612-8323
Shin-Ichi UsamiDepartment of Hearing Implant Sciences, Shinshu University School of Medicine, Matsumoto 390-8621, Japan.ORCID 0000-0002-5068-6122

Funding

Japan Agency for Medical Research and Development JP16kk0205010, JP18ek0109363, JP21ek0109542, JP24ek0109741Ministry of Health, Labor and Welfare of Japan 20FC1048, 23FC0201Wellcome Trust FC001048
6 · The paper itself

Abstract

BACKGROUND/

objectivesThe

methodsIn this study, we analyzed 7065 patients with non-syndromic hearing loss (mean age 26.4 ± 22.9 years, 2988 male, 3855 female, and 222 without gender information) using massively parallel DNA sequencing for 158 target deafness genes. We identified the patients with biallelic

resultsAmong the 7065 patients, we identified 14 possibly disease-causing

conclusionsWe confirmed non-progressive, mild-to-moderate hearing loss as the clinical characteristics of

Indexed as

Hearing LossHearing Loss, SensorineuralAdolescentAdultChildChild, PreschoolCohort StudiesEast Asian PeopleFemaleHumansJapanMaleMiddle AgedMutationYoung Adultcongenital hearing lossDFNB18Bmild-to moderate hearing lossnon-progressive hearing lossnon-syndromic hearing lossOTOGotogelin

Identifiers

PMID39858607
PMCPMC11765236

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.