Evidence map›Paper›PMID 39859308›Full record

ReviewInternational journal of molecular sciences2025

How Will Nanomedicine Revolutionize Future Dentistry and Periodontal Therapy?

Emira D'Amico, Gitana Maria Aceto, Morena Petrini, Chiara Cinquini, Simonetta D'Ercole, Giovanna Iezzi, Tania Vanessa Pierfelice

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emira D'AmicoDepartment of Medical, Oral and Biotechnological Sciences, University "G. d'Annunzio", via dei Vestini 31, 66013 Chieti, Italy.ORCID 0000-0003-2414-7130
Gitana Maria AcetoDepartment of Medical, Oral and Biotechnological Sciences, University "G. d'Annunzio", via dei Vestini 31, 66013 Chieti, Italy.ORCID 0000-0002-6845-1321
Morena PetriniDepartment of Medical, Oral and Biotechnological Sciences, University "G. d'Annunzio", via dei Vestini 31, 66013 Chieti, Italy.ORCID 0000-0002-3849-4304
Chiara CinquiniDepartment of Surgical, Medical, Molecular Pathologies and of the Critical Area, University of Pisa, Lungarno Antonio Pacinotti, 43, 56126 Pisa, Italy.ORCID 0000-0002-4971-9361
Simonetta D'ErcoleDepartment of Medical, Oral and Biotechnological Sciences, University "G. d'Annunzio", via dei Vestini 31, 66013 Chieti, Italy.ORCID 0000-0002-4797-4019
Giovanna IezziDepartment of Medical, Oral and Biotechnological Sciences, University "G. d'Annunzio", via dei Vestini 31, 66013 Chieti, Italy.
Tania Vanessa PierfeliceDepartment of Medical, Oral and Biotechnological Sciences, University "G. d'Annunzio", via dei Vestini 31, 66013 Chieti, Italy.ORCID 0000-0002-5886-2186

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontitis is a prevalent inflammatory disease affecting the supporting structures of the teeth, leading to gum recession, tooth loss, and systemic health complications. Traditional diagnostic methods and treatments, such as clinical evaluation and scaling, often fall short in early detection and targeted therapy, particularly in complex or advanced cases. Recent advancements in nanomedicine offer promising solutions for improving both the diagnosis and treatment of periodontitis. Nanoparticles, such as liposomes, quantum dots, and nanorods, have demonstrated potential in enhancing diagnostic accuracy by enabling more precise detection of periodontal pathogens and biomarkers at the molecular level. Furthermore, nanotechnology-based therapies, including drug delivery systems and antimicrobial agents, offer localized and controlled release of therapeutic agents, enhancing efficacy and reducing side effects compared to conventional treatments. This study reviews the current applications of nanomedicine in the diagnosis and treatment of periodontitis, highlighting its potential to revolutionize periodontal care by improving early detection, reducing treatment times, and enhancing therapeutic outcomes.

Indexed as

DentistryNanomedicinePeriodontal DiseasesPeriodontitisAnimalsDrug Delivery SystemsHumansNanoparticlesantibacterial activityanti-inflammatory activitydiagnostic activitynanoparticlesperiodontal regenerationperiodontitis

Identifiers

PMID39859308
PMCPMC11765319

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.