Evidence map›Paper›PMID 39859478›Full record

ArticleInternational journal of molecular sciences2025

Expression of

Wojciech Tynior, Dorota Hudy, Karolina Gołąbek, Agnieszka Raczkowska-Siostrzonek, Joanna Katarzyna Strzelczyk

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. [Oral homeostasis imbalance under hypoxia].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wojciech TyniorDepartment of Medical and Molecular Biology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 19 Jordana St., 41-808 Zabrze, Poland.ORCID 0000-0002-0369-3821
Dorota HudyDepartment of Medical and Molecular Biology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 19 Jordana St., 41-808 Zabrze, Poland.ORCID 0000-0002-9110-2314
Karolina GołąbekDepartment of Medical and Molecular Biology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 19 Jordana St., 41-808 Zabrze, Poland.ORCID 0000-0002-0042-5856
Agnieszka Raczkowska-SiostrzonekDepartment of Dental Surgery, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 17 Plac Akademicki, 41-902 Bytom, Poland.
Joanna Katarzyna StrzelczykDepartment of Medical and Molecular Biology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 19 Jordana St., 41-808 Zabrze, Poland.ORCID 0000-0002-3686-5685

Funding

Medical University of Silesia PCN-1-014/N/1/I
6 · The paper itself

Abstract

Molar incisor hypomineralization (MIH) is a developmental defect that affects the enamel tissue of permanent teeth. Clinicians may observe a range of opacities in the affected teeth, varying from white to creamy, yellow, and brown. Of particular interest is an etiology of MIH that has not been rigorously elucidated. Researchers believe that there are many potential etiological factors with strong genetic and/or epigenetic influence. The primary factors contributing to the risk of MIH development include specific medical conditions and circumstances. These encompass prematurity, cesarean delivery, perinatal hypoxia, and various health issues such as measles, urinary tract infections, otitis media, gastrointestinal disorders, bronchitis, kidney diseases, pneumonia, and asthma. Although genetic research in this area has received substantial attention, the investigation of epigenetic factors remains comparatively underexplored. Special attention is given to genes and their protein products involved in amelogenesis. Examples of such genes are

Indexed as

AmelogeninDental Enamel HypoplasiaDental Enamel ProteinsEpithelial CellsMatrix Metalloproteinase 20Mouth MucosaAdolescentAmelogenesisChildExtracellular Matrix ProteinsFemaleHumansMaleMolar HypomineralizationPilot ProjectsProteinsAMBN protein, humanAmelogeninAMELX protein, humanDental Enamel ProteinsENAM protein, humanExtracellular Matrix ProteinsFAM83H protein, humanMatrix Metalloproteinase 20MMP20 protein, humanProteinstuftelinAMBNAMELXENAMFAM83Hgenes expressionMIHMMP20molar incisor hypomineralizationTUFT1

Identifiers

PMID39859478
PMCPMC11766068

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.