Evidence map›Paper›PMID 39860094›Full record

ArticleMolecules (Basel, Switzerland)2025

Characterization and Otoprotective Effects of Polysaccharides from

Matteo Banti, Mercedes Garcia-Gil, Lorenzo Guidotti, Graziano Di Giuseppe, Simona Rapposelli, Daniela Monti, Silvia Tampucci, Marinella De Leo, Francesca Gado, Paola Nieri and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. In Vivo and In Vitro Antioxidant Effects ofAntioxidants (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Matteo BantiDepartment of Pharmacy, University of Pisa, Via Bonanno, 6, 56126 Pisa, Italy.
Mercedes Garcia-GilDepartment of Biology, University of Pisa, Via Luca Ghini, 13, 56126 Pisa, Italy.ORCID 0000-0002-1344-2786
Lorenzo GuidottiDepartment of Biology, University of Pisa, Via Luca Ghini, 13, 56126 Pisa, Italy.ORCID 0009-0000-8335-4821
Graziano Di GiuseppeDepartment of Biology, University of Pisa, Via Luca Ghini, 13, 56126 Pisa, Italy.ORCID 0000-0002-9999-7650
Simona RapposelliDepartment of Pharmacy, University of Pisa, Via Bonanno, 6, 56126 Pisa, Italy.ORCID 0000-0003-0146-6358
Daniela MontiDepartment of Pharmacy, University of Pisa, Via Bonanno, 6, 56126 Pisa, Italy.ORCID 0000-0001-7622-4367
Silvia TampucciDepartment of Pharmacy, University of Pisa, Via Bonanno, 6, 56126 Pisa, Italy.ORCID 0000-0002-8927-6083
Marinella De LeoDepartment of Pharmacy, University of Pisa, Via Bonanno, 6, 56126 Pisa, Italy.ORCID 0000-0002-5544-8457
Francesca GadoDepartment of Pharmaceutical Sciences, University of Milan, 20133 Milan, Italy.ORCID 0000-0003-2971-0834
Paola NieriDepartment of Pharmacy, University of Pisa, Via Bonanno, 6, 56126 Pisa, Italy.ORCID 0000-0001-5809-2938
Clementina ManeraDepartment of Pharmacy, University of Pisa, Via Bonanno, 6, 56126 Pisa, Italy.

Funding

Italian Ministry of University and Research no number
6 · The paper itself

Abstract

Hearing loss is one of the most common sensory disorders in humans, and a large number of cases are due to ear cell damage caused by ototoxic drugs including anticancer agents, such as cisplatin. The recent literature reported that hearing loss is promoted by an excessive generation of reactive oxygen species (ROS) in cochlea cells, which causes oxidative stress. Recently, polysaccharides from the cyanobacterium

Indexed as

PolysaccharidesPolysaccharides, BacterialProtective AgentsSpirulinaAnimalsAntineoplastic AgentsAntioxidantsCell LineCell SurvivalCisplatinHumansMiceOrgan of CortiOxidative StressReactive Oxygen SpeciesAntineoplastic AgentsAntioxidantsCisplatinPolysaccharidesPolysaccharides, BacterialProtective AgentsReactive Oxygen SpeciesArthrospira (Spirulina) platensisLC-MSmicroalgaeotoprotective effectpolysaccharidesradical scavenging activity

Identifiers

PMID39860094
PMCPMC11767895

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.