Evidence map›Paper›PMID 39861217›Full record

ReviewPolymers2025

Advancements in Oral Delivery Systems for Probiotics Based on Polysaccharides.

Zi-Dan Wang, Wei Zhang, Tian-Xin Liang

Abstract readReview
In one paragraph

Review in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Assessing the Impact ofNutrients · 2026
    Trial
  2. Review
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  4. Review
  5. Article
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zi-Dan WangCollege of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0003-1266-5926
Wei ZhangCollege of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310058, China.
Tian-Xin LiangCollege of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310058, China.ORCID 0009-0008-4963-8503

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Probiotics are an essential dietary supplement for intestinal flora balance, inhibition of pathogenic bacteria and immune regulation. However, probiotic inactivation during gastrointestinal transportation remains a big challenge for oral administration. Hence, oral delivery systems (ODSs) based on polysaccharides have been constructed to protect probiotics from harsh environments. Cellulose, chitosan, alginate and their derivates have been used to form a protective layer for probiotics. This review summarizes the superiority and application of polysaccharides in forming protective layers for probiotics. Meanwhile, ODS processes including extrusion, emulsion and spray drying are also summarized. The preparation technique mechanism, the microparticle formation process and especially the role polysaccharides serve in the preparation process are overviewed. Lastly, the need for cell viability retention during the dehydration and construction of core-shell ODS microparticles is emphasized in this review.

Indexed as

microparticleoral delivery systempolysaccharideprobioticstechnology

Identifiers

PMID39861217
PMCPMC11768238

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.