Trial reportNutrients2025
Effects of Short-Term Low Energy Availability on Metabolism and Performance-Related Parameters in Physically Active Adults.
Trial report in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- The Influence of Short-Term, Severe Low Energy Availability With Varying Protein Content on Substrate Metabolism, High-Intensity Exercise Performance and Subjective Responses in Young Adults.European journal of sport science · 2026Trial
- Fueling Women's Football: Evidence-Informed Practical Nutrition Strategies for Performance and Health.Sports medicine (Auckland, N.Z.) · 2026Review
- Optimizing Athlete Travel for Performance: A Scientific Blueprint for Athletes, Coaches, and Sports Medicine Staff.Sports medicine (Auckland, N.Z.) · 2026Review
- Androgen levels of premenopausal females are not observably associated with body composition and physical performance, but may interact with hormonal contraceptive use.European journal of applied physiology · 2026Article
- Rethinking Energy Availability from Conceptual Models to Applied Practice: A Narrative Review.Nutrients · 2026Review
- Protecting women's health in sport: the role of low energy availability in the Female Athlete Triad and RED-S.Frontiers in sports and active living · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesLow energy availability (LEA) can cause impaired reproductive function, bone health issues, and suppressed immune function, and may result in decreased performance and overall health status. The purpose of this study was to investigate adaptions of body composition, blood status, resting metabolic rate, and endurance performance to gain more comprehensive insights into the symptoms of LEA and the adaptive effects in the athlete population (active women (n = 11) and men (n = 11)).
methodsThree treatments were defined as 45 (EA45, control), 30 (EA30), and 10 (EA10) kcal/kg FFM/day and randomly assigned. Pre- and post-intervention measurements were performed through blood sampling, bioelectrical impedance analysis, resting metabolic rate measurement, the oral glucose tolerance test (OGTT), and the incremental endurance test to exhaustion.
resultsThere was a significant reduction in body weight and fat mass in EA10 compared to EA45 (
conclusionsIn conclusion, this short-term study indicates that energy restriction can lead to several metabolic-related adaptations, which suggests that the availability and regulation of glucose and fats are significantly influenced after only five days of LEA in physically active women and men. Future research should focus on longer exposures of LEA and sex-specific comparisons (including the menstrual cycle) on LEA symptoms.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.