Evidence map›Paper›PMID 39861414›Full record

SynthesisNutrients2025

Efficacy of

Isabel Viña, Juan R Viña, Macarena Carranza, Gonzalo Mariscal

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Isabel ViñaIVB Wellness Lab, C/Colón 12, 46004 Valencia, Spain.ORCID 0009-0001-6571-152X
Juan R ViñaDepartamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto INCLIVA, Universitat de València, 46010 Valencia, Spain.
Macarena CarranzaIVB Wellness Lab, C/Colón 12, 46004 Valencia, Spain.
Gonzalo MariscalSchool of Medicine, Valencia Catholic University, C/Quevedo 2, 46001 Valencia, Spain.ORCID 0000-0002-5166-198X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolycystic ovary syndrome (PCOS) is a common endocrine disorder that affects women of reproductive age and requires better treatment.

methodsIn accordance with PRISMA standards, this meta-analysis included studies that compared

resultsTwenty-two studies (

conclusionsNAC had a major effect on progesterone, endometrial thickness, and LH levels in women with PCOS. Therefore, it may be a potential treatment option.

Indexed as

AcetylcysteinePolycystic Ovary SyndromeAdultAntioxidantsClomipheneEndometriumFemaleHumansLuteinizing HormoneMetforminProgesteroneTreatment OutcomeAcetylcysteineAntioxidantsClomipheneLuteinizing HormoneMetforminProgesteronefertilitymetforminNACN-acetylcysteinePCOSpolycystic ovary syndrome

Identifiers

PMID39861414
PMCPMC11768055

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.