Evidence map›Paper›PMID 39861449›Full record

Trial reportNutrients2025

Beneficial Effects of a Moderately High-Protein Diet on Telomere Length in Subjects with Overweight or Obesity.

Blanca De la Fuente, Fermín I Milagro, Marta Cuervo, José A Martínez, José I Riezu-Boj, Guillermo Zalba, Amelia Marti Del Moral, Sonia García-Calzón

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Blanca De la FuenteDepartment of Nutrition, Food Sciences and Physiology, Center for Nutrition and Research, University of Navarra, 31008 Pamplona, Spain.
Fermín I MilagroDepartment of Nutrition, Food Sciences and Physiology, Center for Nutrition and Research, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-3228-9916
Marta CuervoDepartment of Nutrition, Food Sciences and Physiology, Center for Nutrition and Research, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0003-2082-224X
José A MartínezDepartment of Nutrition, Food Sciences and Physiology, Center for Nutrition and Research, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0001-5218-6941
José I Riezu-BojDepartment of Nutrition, Food Sciences and Physiology, Center for Nutrition and Research, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-1885-8457
Guillermo ZalbaDepartment of Biochemistry and Genetics, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0003-4616-1523
Amelia Marti Del MoralDepartment of Nutrition, Food Sciences and Physiology, Center for Nutrition and Research, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0001-9832-7981
Sonia García-CalzónDepartment of Nutrition, Food Sciences and Physiology, Center for Nutrition and Research, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-1249-4795

Funding

Gobierno de Navarra PT024Ministerio de Ciencia, Innovación y Universidades IJC2019-040796-ISpanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition CB12/03/30002
6 · The paper itself

Abstract

BACKGROUND AND

aimTelomere length (TL) is a key biomarker of cellular aging, with shorter telomeres associated with age-related diseases. Lifestyle interventions mitigating telomere shortening are essential for preventing such conditions. This study aimed to examine the effects of two weight loss dietary strategies, based on a moderately high-protein (MHP) diet and a low-fat (LF) diet on TL in individuals with overweight or obesity. METHODS AND

resultsA total of 164 participants, aged 18-65 years from the OBEKIT trial received the MHP (

conclusionThis study shows that a MHP diet may have a protective effect on TL during weight loss, particularly in women, potentially contributing to healthier aging. These results highlight the importance of considering macronutrient composition in dietary interventions aimed at preserving TL.

Indexed as

Dietary ProteinsDiet, High-ProteinObesityOverweightTelomereTelomere HomeostasisTelomere ShorteningAdolescentAdultAgedDiet, Fat-RestrictedFemaleHumansMaleMiddle AgedWeight LossDietary Proteinscalorie restrictiondietary interventionshigh-protein dietlow-fat dietmacronutrient distributiontelomeres

Identifiers

PMID39861449
PMCPMC11767735

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.