Evidence map›Paper›PMID 39861452›Full record

ArticleNutrients2025

Egg Consumption and Mortality: A Prospective Cohort Study of Australian Community-Dwelling Older Adults.

Holly Wild, Danijela Gasevic, Robyn L Woods, Joanne Ryan, Rory Wolfe, Yuquan Chen, Thara Govindaraju, John J McNeil, Tracy McCaffrey, Lawrence J Beilin and 2 more

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Holly WildSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.ORCID 0000-0002-7492-6709
Danijela GasevicSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.ORCID 0000-0001-5976-4011
Robyn L WoodsSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.ORCID 0000-0003-1249-6149
Joanne RyanSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.ORCID 0000-0002-7039-6325
Rory WolfeSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.
Yuquan ChenSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.ORCID 0000-0001-5792-6566
Thara GovindarajuSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.
John J McNeilSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.ORCID 0000-0002-1049-5129
Tracy McCaffreyDepartment of Nutrition, Dietetics and Food, Monash University, Notting Hill, VIC 3168, Australia.ORCID 0000-0001-9699-3083
Lawrence J BeilinMedical School, University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0003-4853-7360
Dragan IlicSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.
Alice J OwenSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.ORCID 0000-0002-4807-6069

Funding

ASPirin in Reducing Events in the ElderlyU01AG029824 · NIA · HENNEPIN HEALTHCARE RESEARCH INSTITUTE · PI MCNEIL, JOHN JAMES, MURRAY, ANNE M · 2009 to 2018
$64.6M
Main Administrative CoreU19AG062682 · NIA · HENNEPIN HEALTHCARE RESEARCH INSTITUTE · PI CHAN, ANDREW T, MCNEIL, JOHN JAMES · 2019 to 2023
$42.9M
NIA NIH HHS U01 AG029824NIA NIH HHS U19 AG062682
6 · The paper itself

Abstract

BACKGROUND/

objectivesEgg consumption in adults has been linked with a modestly increased risk of all-cause and CVD mortality. However, evidence on adults aged 65 y+ is limited. The objective of this study was to investigate the association between egg intake and mortality in community-dwelling older adults.

methodsIn this prospective cohort study, 8756 adults aged 70+ years, participants in the ASPirin in Reducing Events in the Elderly (ASPREE) Longitudinal Study of Older Persons, self-reported the frequency of their total egg intake: never/infrequently (rarely/never, 1-2 times/month), weekly (1-6 times/week), and daily (daily/several times per day). All-cause and cause-specific (cardiovascular disease [CVD] and cancer) mortality was established from at least two sources: medical records, death notices, next of kin, or death registry linkage. The association between egg intake and mortality was assessed using Cox proportional hazards regression analysis, adjusted for socio-demographic, health-related, and clinical factors and overall dietary quality.

resultsOver the median 5.9-year follow-up period, a total of 1034 all-cause deaths (11.8%) were documented. A 29% lower risk of CVD mortality (HR (95% CI): 0.71 [0.54-0.92]) and a 17% (HR (95% CI): 0.83 [0.71-0.96]) lower risk of all-cause mortality were observed among those who consumed eggs weekly, compared to those who consumed eggs never/infrequently; no statistically significant association was observed for weekly consumption and cancer mortality. In contrast, compared to those that never or infrequently consumed eggs, daily consumption had slightly higher odds of mortality, though these results did not reach statistical significance.

conclusionsThe consumption of eggs 1-6 times per week was associated with a lower risk of all-cause mortality and CVD mortality in community-dwelling adults aged 70 years and over. These findings may be important to inform the development of evidence-based guidelines for egg consumption.

Indexed as

Cardiovascular DiseasesDietEggsIndependent LivingMortalityAgedAged, 80 and overAustraliaCause of DeathFemaleHumansLongitudinal StudiesMaleNeoplasmsProportional Hazards ModelsProspective Studiesegg consumptioneggshealthy ageingnutritionolder adults

Identifiers

PMID39861452
PMCPMC11767731

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.