Evidence map›Paper›PMID 39864784›Full record

Observational studyJournal of affective disorders2025

Obsessive-compulsive symptoms in individuals with a history of eating disorders.

Avantika Kapadia, Laura M Thornton, Melissa A Munn-Chernoff, Amitai Abramovitch, Dean McKay, Jonathan S Abramowitz, Zeynep Yilmaz, James J Crowley, Cynthia M Bulik, Hunna J Watson

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of affective disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Associations Between Avoidant/Restrictive Food Intake Disorder Dimensions and Obsessive-Compulsive Symptomatology.European eating disorders review : the journal of the Eating Disorders Association · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Avantika KapadiaDepartment of Psychological and Brain Sciences, University of Louisville, Louisville, KY, USA. Electronic address: avantika.kapadia@louisville.edu.
Laura M ThorntonDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: laura_thornton@med.unc.edu.
Melissa A Munn-ChernoffDepartment of Community, Family, and Addiction Sciences, Texas Tech University, Lubbock, TX, USA. Electronic address: melissa.chernoff@ttu.edu.
Amitai AbramovitchDepartment of Psychology, Texas State University, San Marcos, TX, USA. Electronic address: abramovitch@txstate.edu.
Dean McKayDepartment of Psychology, Fordham University, Bronx, NY, USA. Electronic address: mckay@fordham.edu.
Jonathan S AbramowitzDepartment of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: jabramowitz@unc.edu.
Zeynep YilmazDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; National Centre for Register-based Research, Aarhus BSS, Aarhus University, Aarhus, Denmark; Department of Biomedicine, Aarhus University, Aarhus, Denmark; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. Electronic address: zyilmaz.ncrr@au.dk.
James J CrowleyDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: crowley@unc.edu.
Cynthia M BulikDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: cynthia_bulik@med.unc.edu.
Hunna J WatsonDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; School of Population Health, Curtin University, Perth, Western Australia, Australia; Division of Paediatrics, School of Medicine, The University of Western Australia, Perth, Western Australia, Australia. Electronic address: hunna_watson@med.unc.edu.

Funding

North Carolina Translational & Clinical Sciences Institute (NC TraCS)UL1TR001111 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$43.9M
Eating Disorders Genetics Initiative (EDGI)R01MH120170 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BULIK, CYNTHIA M · 2019 to 2023
$7.2M
1/3 Eating Disorders Genetics Initiative 2 (EDGI2)R01MH136149 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CYNTHIA M BULIK, Laura Marianne Huckins · 2024 to 2026
$5.1M
1/7 PGC: Advancing Discovery and ImpactR01MH124871 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BULIK, CYNTHIA M, SULLIVAN, PATRICK F · 2021 to 2025
$3.5M
OCD: Novel Comparative Genomic Approaches to Identify Disease and Treatment MechanismsR01MH110427 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CROWLEY, JAMES JOSEPH · 2016 to 2021
$3.0M
2/2 Rare Genetic Variation and Risk for Obsessive Compulsive DisorderR01MH124675 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CROWLEY, JAMES JOSEPH · 2021 to 2025
$743k
NCATS NIH HHS UL1 TR001111NIMH NIH HHS R01 MH110427NIMH NIH HHS R01 MH120170NIMH NIH HHS R01 MH124675NIMH NIH HHS R01 MH124871NIMH NIH HHS R01 MH136149
6 · The paper itself

Abstract

backgroundOCD symptoms are well documented in anorexia nervosa (AN) and to a lesser extent in bulimia nervosa (BN), yet remain virtually unstudied in binge-eating disorder (BED).

methodsIn this cross-sectional observational study, 5927 participants with lifetime eating disorders (EDs) (i.e., past or current) were categorized into five groups based on their diagnostic histories: AN only (n = 2330), BN only (n = 740), BED only (n = 665), AN and another ED diagnosis (AN Mixed) (n = 1293), and BN and BED (BN-BED) (n = 899). Obsessive-Compulsive Inventory-12 scores were compared across these groups and with OCD (n = 1040), anxiety-related disorders (ANX) (n = 423), and non-clinical community (NCC) (n = 1194) cohorts.

resultsOCD symptoms were common among individuals with lifetime AN, BN, BED, and multiple EDs, with obsessing being the most prevalent dimension, followed by ordering, checking, and washing. The obsessing scale, which captures general intrusive thoughts rather than traditional OCD obsessions, was notably high. ED groups generally scored higher on the OCI-12 subscales than the ANX and NCC cohorts but lower than the OCD cohort, although ordering severity was higher in some ED groups. Positive correlations were found between ED symptoms and OCI-12 subscales, and gender-diverse individuals and men had greater OCD symptoms than women.

conclusionsClinicians should be vigilant for OCD symptoms in individuals with AN, BN, and BED. These findings call for research on the mechanisms linking EDs and OCD symptoms and support integrated treatment approaches for both conditions.

Indexed as

Bulimia NervosaFeeding and Eating DisordersObsessive-Compulsive DisorderAdolescentAdultAnorexia NervosaBinge-Eating DisorderCross-Sectional StudiesFemaleHumansMaleMiddle AgedPsychiatric Status Rating ScalesYoung AdultAnorexia nervosaBinge-eating disorderBulimia nervosaComorbidityEating disordersGenderObsessive-compulsive disorder symptoms

Identifiers

PMID39864784
PMCPMC11952142

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.