Evidence map›Paper›PMID 39865159›Full record

ArticlePediatric nephrology (Berlin, Germany)2025

Factors associated with statural growth in pediatric kidney transplant recipients with focus on metabolic acidosis.

Agnieszka Prytuła, Dries Reynders, Els Goetghebeur, Kai Krupka, Justine Bacchetta, Nele Kanzelmeyer, Isabella Guzzo, Raffaella Labbadia, Elisa Benetti, Mohan Shenoy and 12 more

Abstract read
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In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Agnieszka PrytułaDepartment of Pediatric Nephrology and Rheumatology, ERKNet Center, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium. agnieszka.prytula@uzgent.be.ORCID http://orcid.org/0000-0001-9551-8758
Dries ReyndersDepartment of Applied Mathematics, Computer Science and Statistics, Ghent University, Ghent, Belgium.
Els GoetghebeurDepartment of Applied Mathematics, Computer Science and Statistics, Ghent University, Ghent, Belgium.
Kai KrupkaCERTAIN Research Network, Heidelberg, Germany.
Justine BacchettaDepartment of Pediatric Nephrology and Rheumatology, CHU de Lyon, Bron, France.
Nele KanzelmeyerDepartment of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany.
Isabella GuzzoDialysis and Renal Transplant Unit, Bambino Gesù Children's Research Hospital Istituto Di Ricovero E Cura a Carattere Scientifico, Rome, Italy.
Raffaella LabbadiaDialysis and Renal Transplant Unit, Bambino Gesù Children's Research Hospital Istituto Di Ricovero E Cura a Carattere Scientifico, Rome, Italy.
Elisa BenettiPediatric Nephrology, Laboratory of Immunopathology and Molecular Biology of the Kidney, Department of Women's and Children's Health, Padua University Hospital, Padua, Italy.
Mohan ShenoyRoyal Manchester Children's Hospital, Manchester, UK.
Anne-Laure Sellier-LeclercDepartment of Pediatric Nephrology and Rheumatology, CHU de Lyon, Bron, France.
Jun OhDepartment of Pediatric Nephrology and Transplantation, University Children's Hospital, University Medical Center Hamburg/Eppendorf, Hamburg, Germany.
Mieczysław LitwinDepartment of Nephrology, Kidney Transplantation and Arterial Hypertension, Children's Memorial Health Institute, Warsaw, Poland.
Jacek RubikDepartment of Nephrology, Kidney Transplantation and Arterial Hypertension, Children's Memorial Health Institute, Warsaw, Poland.
Atif AwanDepartment of Nephrology and Transplantation, Temple Street, Dublin, Ireland.
Ilmay BilgeDepartment of Pediatric Nephrology, Koç University, Istanbul, Turkey.
Lutz T WeberPediatric Nephrology, Faculty of Medicine, Children's and Adolescents' Hospital, University Hospital of Cologne, University of Cologne, Cologne, Germany.
Dominik MüllerDepartment of Pediatrics, Charité University Hospital, Berlin, Germany.
Thomas SimonDepartment of Pediatric Nephrology, University Hospital Toulouse, Toulouse, France.
Lars PapeDepartment of Pediatrics II, University Hospital of Essen, Essen, Germany.
Burkhard TönshoffCERTAIN Research Network, Heidelberg, Germany.
on behalf of the ESPN Transplantation and CKD-MBD working group and, the CERTAIN Research Network

Funding

ESPN 2023-01
6 · The paper itself

Abstract

backgroundWe investigated factors associated with post-transplant growth in pediatric kidney transplant (KTx) recipients with a focus on plasma bicarbonate (HCO3

methodsIn this study of the CERTAIN Registry, data were collected up to 5 years post-transplant. Generalized Additive Mixed Models were applied to assess the association between post-transplant growth and covariates. A trial-emulation analysis was performed to estimate the causal effect of alkali supplementation on growth.

resultsWe report on 2147 primary KTx recipients with a median age at KTx of 10.2 (IQR 5.1;14.3) years. No statistically significant association was found between growth and HCO3

conclusionsWe found no association between HCO3

Indexed as

AcidosisBicarbonatesKidney TransplantationAdolescentChildChild, PreschoolFemaleGraft RejectionHumansMaleRegistriesRetrospective StudiesBicarbonatesKidney transplantationMetabolic acidosisPediatricStatural growth

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.