Evidence map›Paper›PMID 39865267›Full record

Trial reportBMC medicine2025

Persistent effect of salt reduction in schoolchildren and their families: 1-year follow-up after an application-based cluster randomized controlled trial.

Yuan Li, Puhong Zhang, Feng J He, Rong Luo, Jing Song, Changqiong Wang, Fengge Chen, Wei Zhao, Yuhong Zhao, Hang Chen and 5 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yuan LiThe George Institute for Global Health, Beijing, China.ORCID http://orcid.org/0000-0003-1887-7065
Puhong ZhangThe George Institute for Global Health, Beijing, China. zpuhong@georgeinstitute.org.cn.ORCID http://orcid.org/0000-0003-4610-9848
Feng J HeWolfson Institute of Population Health, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, London, UK.ORCID http://orcid.org/0000-0003-2807-4119
Rong LuoThe George Institute for Global Health, Beijing, China.
Jing SongWolfson Institute of Population Health, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, London, UK.
Changqiong WangWolfson Institute of Population Health, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, London, UK.
Fengge ChenShijiangzhuang Centre for Disease Control and Prevention, Shijiazhuang, Hebei Province, China.
Wei ZhaoShijiangzhuang Centre for Disease Control and Prevention, Shijiazhuang, Hebei Province, China.
Yuhong ZhaoCentre for Disease Control and Prevention, Shijiazhuang, Hebei Province, China.
Hang ChenLuzhou Centre for Disease Control and Prevention, Luzhou, Sichuan Province, China.
Tianyong WuLuzhou Centre for Disease Control and Prevention, Luzhou, Sichuan Province, China.
Xiaoyan WangLuzhou Centre for Disease Control and Prevention, Luzhou, Sichuan Province, China.
Hui ZhouYueyang Centre for Disease Control and Prevention, Yueyang, Hunan Province, China.
Zhi HanYueyang Centre for Disease Control and Prevention, Yueyang, Hunan Province, China.
Jie ZhangYueyang Centre for Disease Control and Prevention, Yueyang, Hunan Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA 12-month cluster randomized controlled trial (RCT) demonstrated the effectiveness of an application-based education program in reducing the salt intake and systolic blood pressure (SBP) of schoolchildren's adult family members. This study aimed to assess whether the effect at 12 months persisted at 24 months.

methodsFifty-four schools were randomly assigned to either the intervention or control group. All participants (594 children in grade 3 and 1188 of their adult family members) who completed the baseline survey were contacted again 12 months after the trial. The primary outcome was the difference in salt intake change between the intervention and control groups at 24 months versus baseline and 12 months, measured by the mean two consecutive 24-h urinary sodium excretions. The secondary outcome was the difference in the change of blood pressure and salt-related Knowledge, Attitude, Practice (KAP) score.

resultsThe difference in salt intake change in adults between the intervention and control groups after adjusting for confounding factors was - 0.38 g/day at 24 months versus baseline (95% CI - 0.81 to 0.05, p = 0.09), following the - 0.83 g/day (95% CI - 1.25 to - 0.41, p < 0.001) at 12 months. The adjusted difference in SBP change was - 2.19 mm Hg (95% CI - 3.63 to - 0.76, p = 0.003) at 24 months versus baseline, following the - 1.80 mm Hg (95% CI - 3.19 to - 0.40, p = 0.01) at 12 months. The intervention group had a higher KAP score than the control group both at 12 months and at 24 months versus baseline. No significant changes were found in children.

conclusionsThe effect of the education program on adults' salt intake faded, but the SBP lowering effect and the improvement of KAP score remained 12 months after the completion of the RCT. Continuous efforts are needed to maintain the salt reduction effects in real-world settings.

trial registrationChiCTR1800017553. Registered on August 3, 2018.

Indexed as

Diet, Sodium-RestrictedHealth EducationSodium Chloride, DietaryAdolescentAdultBlood PressureChildFamilyFemaleFollow-Up StudiesHealth Knowledge, Attitudes, PracticeHumansMaleSodium Chloride, DietaryBlood pressureFollow-upPersistent effectSalt reduction

Identifiers

PMID39865267
PMCPMC11771009

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.