Evidence map›Paper›PMID 39866411›Full record

ArticleHeliyon2025

Ya That Somdun improves hepatic steatosis in hyperlipidemic rats.

Suchittra Samuhasaneeto, Gorawit Yusakul, Chuchard Punsawad, Kingkan Bunluepuech

Abstract read
In one paragraph

Article in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Suchittra SamuhasaneetoSchool of Medicine, Walailak University, Nakhon Si Thammarat, 80160, Thailand.
Gorawit YusakulSchool of Pharmacy, Walailak University, Nakhon Si Thammarat, 80160, Thailand.
Chuchard PunsawadSchool of Medicine, Walailak University, Nakhon Si Thammarat, 80160, Thailand.
Kingkan BunluepuechSchool of Medicine, Walailak University, Nakhon Si Thammarat, 80160, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ya That Somdun (YTS) is a traditional Thai medicine composed of six herbs used as a strengthening tonic. Some of the herbs constituting YTS have antihyperlipidemic and anti-obesity activities. The objective of this study was to elucidate the antihyperlipidemic properties of YTS extract in rats with cholesterol suspension-induced hyperlipidemia. Male Sprague-Dawley rats were subdivided into four groups: normal control (NC), hyperlipidemic control (HC), and those who were administered 100 (YTS100) and 200 mg (YTS200) of YTS/kg body weight (BW). Hyperlipidemic rats were orally administered YTS extract for four consecutive weeks from the fifth week of cholesterol suspension. Serum lipid profiles, body weights, liver and renal functional markers, gene expression involved in lipid metabolism, and liver histopathology were examined. The HC and YTS groups showed a significant increase in body weights compared with the NC group. The YTS100 and YTS200 groups showed no significant difference in serum triglyceride, total cholesterol, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) levels compared with the NC and HC groups. YTS treatment (100 mg/kg BW) downregulated sterol regulatory element binding protein 1c (

Indexed as

Hyperlipidemic ratsSterol regulatory element binding protein 1c (SREBP-1c)Traditional Thai medicineYa That somdun

Identifiers

PMID39866411
PMCPMC11758198

What Socratic holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.