Evidence map›Paper›PMID 39867974›Full record

ArticleClinical, cosmetic and investigational dermatology2025

Evaluation of the Effectiveness of Using LED Light Combined With Chromophore Gel in Treating Acne Vulgaris - Preliminary Study.

Anna Ewa Deda, Magdalena Hartman-Petrycka, Sławomir Wilczyński

Abstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anna Ewa DedaDepartment of Practical Cosmetology and Skin Diagnostics, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, Sosnowiec, Poland.
Magdalena Hartman-PetryckaDepartment of Basic Biomedical Science, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, Sosnowiec, Poland.
Sławomir WilczyńskiDepartment of Basic Biomedical Science, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, Sosnowiec, Poland.ORCID 0000-0002-6066-3127

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The aim was to quantitatively evaluate the effectiveness of LED light therapy combined with photoacceptor substances having anti-acne properties in reducing the symptoms of acne vulgaris. Patients and Methods: 15 subjects aged 20 to 24 who suffered from moderate or severe acne lesions. The treatments were performed using a LED device (465-880 nm). Blue light - 465 nm in combination with red light - 640 nm in pulsed mode and near-infrared light - 880 nm were used in the treatments. Each patient underwent 6 treatments, with intervals between treatments of 7 days. 3D images and biomechanical measurements were performed before first and fourth treatments and 6 weeks after the last. Additionally, photographic documentation was made 7 days after the 6th treatment. Results: The series of treatments significantly influenced the clinical condition of the patients' skin. The treatments had a statistically significant impact on the intensity of erythema on the left and right cheeks. The hydration of the stratum corneum in all the examined areas of the face changed significantly after the treatments. Greater hydration was achieved six weeks after six treatments compared to the values obtained prior to treatment and after three treatments. The activity of sebaceous glands and, consequently, the amount of sebum on the epidermal surface in all the examined areas of the face changed significantly after the treatments. The treatments had a statistically significant impact on the volume of atrophic scars. Conclusion: Therapy combining LED light with photoacceptor substances is an effective method of reducing the symptoms of acne vulgaris. The treatments lead to a significant reduction in erythema, reduction in the volume of atrophic scars, improvement of skin hydration and regulation of sebum secretion. These effects can be identified quantitatively. Further studies are necessary to confirm the long-term effectiveness and safety of this method.

Indexed as

erythemahydrationphototherapysebum

Identifiers

PMID39867974
PMCPMC11766709

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.