Evidence map›Paper›PMID 39868138›Full record

ArticlebioRxiv : the preprint server for biology2025

From Flies to Humans: A Conserved Role of CEBPZ, NOC2L, and NOC3L in rRNA Processing and Tumorigenesis.

Guglielmo Rambaldelli, Valeria Manara, Andrea Vutera Cuda, Giovanni Bertalot, Marianna Penzo, Paola Bellosta

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Guglielmo RambaldelliDepartment of Medical and Surgical Sciences, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy.ORCID 0009-0000-5650-2892
Valeria ManaraDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Via Sommarive 9, 38123 Trento, Italy.ORCID 0000-0001-9292-6588
Andrea Vutera CudaDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Via Sommarive 9, 38123 Trento, Italy.ORCID 0009-0006-8196-9455
Giovanni BertalotDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Via Sommarive 9, 38123 Trento, Italy.ORCID 0000-0002-4862-7705
Marianna PenzoDepartment of Medical and Surgical Sciences, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy.ORCID 0000-0002-1738-9767
Paola BellostaDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Via Sommarive 9, 38123 Trento, Italy.ORCID 0000-0003-1913-5661

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Role of Myc in the Growth Regulation PathwaysSC1DK085047 · NIDDK · CITY COLLEGE OF NEW YORK · PI BELLOSTA, PAOLA BELLOSTA · 2009 to 2010
$738k
NIDDK NIH HHS SC1 DK085047NIH HHS P40 OD018537
6 · The paper itself

Abstract

NOC1, NOC2, and NOC3 are evolutionarily conserved nucleolar proteins that play an essential role in the maturation and processing of ribosomal RNA (rRNA). NOC1, in

Indexed as

CancerCEBPZDrosophilaEvolutionary conservationNOC1/2/3NOC2L/3LNucleolar proteinsRibosome biogenesisrRNA processing

Identifiers

PMID39868138
PMCPMC11761043

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.