Evidence map›Paper›PMID 39868285›Full record

ArticlebioRxiv : the preprint server for biology2025

Functional characterization of eicosanoid signaling in

Daiki Fujinaga, Cebrina Nolan, Naoki Yamanaka

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Daiki FujinagaDepartment of Entomology, Institute for Integrative Genome Biology, University of California, Riverside, Riverside, CA 92521, USA.
Cebrina NolanDepartment of Entomology, Institute for Integrative Genome Biology, University of California, Riverside, Riverside, CA 92521, USA.
Naoki YamanakaDepartment of Entomology, Institute for Integrative Genome Biology, University of California, Riverside, Riverside, CA 92521, USA.ORCID 0000-0002-6244-2686

Funding

Text mining in the CloudU24HG010859 · NHGRI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI CAROL J BULT, PAUL Warren STERNBERG · 2019 to 2026
$42.0M
Resource Project CoreU41HG000739 · NHGRI · HARVARD UNIVERSITY · PI PERRIMON, NORBERT · 2014 to 2022
$32.3M
Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
DROSOPHILA GENOMICS RESOURCE CENTERP40OD010949 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Andrew Zelhof · 2012 to 2026
$9.4M
Membrane steroid hormone transporters in development and reproductionDP2GM132929 · NIGMS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI YAMANAKA, NAOKI · 2018 to 2018
$2.3M
Molecular genetics of signaling lipidsR35GM153331 · NIGMS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI Naoki Yamanaka · 2024 to 2026
$1.2M
NHGRI NIH HHS U24 HG010859NHGRI NIH HHS U41 HG000739NIGMS NIH HHS DP2 GM132929NIGMS NIH HHS R35 GM153331NIH HHS P40 OD010949NIH HHS P40 OD018537
6 · The paper itself

Abstract

20-carbon fatty acid-derived eicosanoids are versatile signaling oxylipins in mammals. In particular, a group of eicosanoids termed prostanoids are involved in multiple physiological processes, such as reproduction and immune responses. Although some eicosanoids such as prostaglandin E2 (PGE2) have been detected in some insect species, molecular mechanisms of eicosanoid synthesis and signal transduction in insects have not been thoroughly investigated. Our phylogenetic analysis indicated that, in clear contrast to the presence of numerous receptors for oxylipins and other lipid mediators in humans, the

Identifiers

PMID39868285
PMCPMC11761813

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.