Evidence map›Paper›PMID 39868305›Full record

ArticlebioRxiv : the preprint server for biology2025

Hypoxia-inducible factor 2α promotes protective Th2 cell responses during intestinal helminth infection.

Jasmine C Labuda, Tayla M Olsen, Sheenam Verma, Samantha Kimmel, Thomas H Edwards, Matthew J Dufort, Oliver J Harrison

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Jasmine C LabudaCenter for Fundamental Immunology, Benaroya Research Institute, Seattle, WA, USA.
Tayla M OlsenCenter for Fundamental Immunology, Benaroya Research Institute, Seattle, WA, USA.
Sheenam VermaCenter for Fundamental Immunology, Benaroya Research Institute, Seattle, WA, USA.
Samantha KimmelCenter for Fundamental Immunology, Benaroya Research Institute, Seattle, WA, USA.
Thomas H EdwardsCenter for Systems Immunology, Benaroya Research Institute, Seattle, WA, USA.
Matthew J DufortCenter for Systems Immunology, Benaroya Research Institute, Seattle, WA, USA.
Oliver J HarrisonCenter for Fundamental Immunology, Benaroya Research Institute, Seattle, WA, USA.ORCID 0000-0003-1515-9586

Funding

Training in Cellular & Molecular BiologyT32GM136534 · NIGMS · UNIVERSITY OF WASHINGTON · PI Andrew Atwell Oberst, LARRY S ZWEIFEL · 2021 to 2026
$5.8M
Commensal-specific T cell function in skin wound repairR01AI158624 · NIAID · BENAROYA RESEARCH INST AT VIRGINIA MASON · PI HARRISON, OLIVER JAMES · 2021 to 2025
$2.9M
NIAID NIH HHS R01 AI158624NIGMS NIH HHS T32 GM136534
6 · The paper itself

Abstract

Th2 cells must sense and adapt to the tissue milieu in order to provide protective host immunity and tissue repair. Here, we examined the mechanisms promoting Th2 cell differentiation and function within the small intestinal lamina propria. Single cell RNA-seq analyses of CD4

Identifiers

PMID39868305
PMCPMC11761574

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.