Evidence mapPaperPMID 39868784Full record

ReviewmBio2025

Extracellular vesicles in malaria: proteomics insights,

Núria Sima, Alberto Ayllon-Hermida, Carmen Fernández-Becerra, Hernando A Del Portillo

Abstract readReview
In one paragraph

Review in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Núria Sima *ISGlobal, Barcelona, Spain.
Alberto Ayllon-Hermida *ISGlobal, Barcelona, Spain.
Carmen Fernández-BecerraISGlobal, Barcelona, Spain.ORCID 0000-0001-5154-0013
Hernando A Del PortilloISGlobal, Barcelona, Spain.ORCID 0000-0002-5278-3452

Funding

Centro de Investigación Biotecnológica en Red de Enfermedades Infecciosas (CIBERINFEC) CB 2021Fundación Ramón Areces (FRA)Government of Catalonia | Agència de Gestió d'Ajuts Universitaris i de Recerca (AGAUR) 2021 SGR 01554'la Caixa' Foundation ('la Caixa') LCF/PR/HR21/52410021MCIN/AEI 10.13039/501100011033 CEX2023-0001290-SSpanish Ministry of Science and Innovation PID2022-142908OB-I00
6 · The paper itself

Abstract

Globally, an estimated 2.1 billion malaria cases and 11.7 million malaria deaths were averted in the period 2000-2022. Noticeably, despite effective control measurements, in 2022 there were an estimated 249 million malaria cases in 85 malaria-endemic countries and an increase of 5 million cases compared with 2021. Further understanding the biology, epidemiology, and pathogenesis of human malaria is therefore essential for achieving malaria elimination. Extracellular vesicles (EVs) are membrane-enclosed nanoparticles pivotal in intercellular communication and secreted by all cell types. Here, we will review what is currently known about EVs in malaria, from biogenesis and cargo to molecular insights of pathophysiology. Of relevance, a meta-analysis of proteomics cargo, and comparisons between

Indexed as

Extracellular VesiclesMalariaProteomicsAnimalsHumansbiomarkersdiagnosisextracellular vesicleskey gapsmalariamolecular cargopathophysiologyvaccines

Identifiers

PMID39868784
PMCPMC11898581

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.