Evidence mapPaperPMID 39871586Full record

ReviewTherapeutic delivery2025

Naturally derived hydrogels for wound healing.

Duy Toan Pham, Ngo Thi Ngoc Thuy, Nguyen Thi Phuong Thao, Le Thi Nhi, Bui Thi Phuong Thuy

Abstract readReview
In one paragraph

Review in Therapeutic delivery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Hydrogel-Based Continuum Soft Robots.Gels (Basel, Switzerland) · 2025
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Duy Toan PhamDepartment of Health Sciences, College of Natural Sciences, Can Tho University, Can Tho, Vietnam.ORCID 0000-0002-8693-3367
Ngo Thi Ngoc ThuyInstitute of Tropical Biology, Vietnam Academy of Science and Technology, Ho Chi Minh City, Vietnam.
Nguyen Thi Phuong ThaoInstitute of Tropical Biology, Vietnam Academy of Science and Technology, Ho Chi Minh City, Vietnam.
Le Thi NhiFaculty of Materials Science, University of Science, Vietnam National University, Ho Chi Minh City, Vietnam.
Bui Thi Phuong ThuyFaculty of Fundamental Sciences, Van Lang University, Ho Chi Minh City, Vietnam.ORCID 0000-0001-5487-414X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural hydrogels have garnered increasing attention due to their natural origins and beneficial roles in wound healing. Hydrogel water-retaining capacity and excellent biocompatibility create an ideal moist environment for wound healing, thereby enhancing cell proliferation and tissue regeneration. For this reason, naturally derived hydrogels formulated from biomaterials such as chitosan, alginate, gelatin, and fibroin are highly promising due to their biodegradability and low immunogenic responses. Recent integrated approaches to utilizing new technologies with bioactive agents have significantly improved the mechanical properties of hydrogels and the controlled release and delivery of active compounds, thereby increasing the efficiency of the treatment processes. Herein, this review highlights the advantages and the challenges of natural hydrogels in wound healing, focusing on their mechanical strength, controlled degradation rates, safety and efficiency validation, and the potential for incorporating advanced technologies such as tissue engineering and gene therapy for utilization in personalized medicine.

Indexed as

Biocompatible MaterialsHydrogelsWound HealingAlginatesAnimalsChitosanGelatinGenetic TherapyHumansTissue EngineeringAlginatesBiocompatible MaterialsChitosanGelatinHydrogelsalginatechitosanfibroingelatinNatural hydrogelswound healing

Identifiers

PMID39871586
PMCPMC11970767

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.