Evidence map›Paper›PMID 39872579›Full record

ArticleCureus2024

Allostatic Load and Oxidative Stress Markers in Women With Early- and Late-Onset Preeclampsia.

Araceli Montoya-Estrada, María Valeria García-Cerda, Alberto Martin Guzmán-Grenfell, Ricardo Figueroa-Damian, José Luis Torres-Cosme, Estibalitz Laresgoiti-Servitje, Jesús Jorge Beltrán-Montoya, José Romo-Yañez, Enrique Reyes-Muñoz

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Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Araceli Montoya-EstradaCoordination of Gynecological and Perinatal Endocrinology, National Institute of Perinatology Isidro Espinosa de los Reyes, Mexico City, MEX.
María Valeria García-CerdaCoordination of Gynecological and Perinatal Endocrinology, National Institute of Perinatology Isidro Espinosa de los Reyes, Mexico City, MEX.
Alberto Martin Guzmán-GrenfellDepartment of Immunobiochemistry, National Institute of Perinatology Isidro Espinosa de los Reyes, Mexico City, MEX.
Ricardo Figueroa-DamianDepartment of Infectology, National Institute of Perinatology Isidro Espinosa de los Reyes, Mexico City, MEX.
José Luis Torres-CosmeResearch Division, Community Interventions, National Institute of Perinatology Isidro Espinosa de los Reyes, Mexico City, MEX.
Estibalitz Laresgoiti-ServitjeResearch Division, National Institute of Perinatology Isidro Espinosa de los Reyes, Mexico City, MEX.
Jesús Jorge Beltrán-MontoyaDepartment of Obstetrics, National Institute of Perinatology Isidro Espinosa de los Reyes, Mexico City, MEX.
José Romo-YañezCoordination of Gynecological and Perinatal Endocrinology, National Institute of Perinatology Isidro Espinosa de los Reyes, Mexico City, MEX.
Enrique Reyes-MuñozCoordination of Gynecological and Perinatal Endocrinology, National Institute of Perinatology Isidro Espinosa de los Reyes, Mexico City, MEX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAllostatic load and oxidative stress (OS) markers differ in women with and without preeclampsia. However, there is no difference in allostatic load and OS markers between late-onset preeclampsia (L-OP) and early-onset preeclampsia (E-OP). This study aimed to compare the concentrations of allostatic load and OS markers in pregnant women with L-OP and E-OP.

methodsThis was a comparative cross-sectional study. Women with single pregnancy and a diagnosis of preeclampsia were included. Women with multiple pregnancies and/or chronic hypertension were excluded. Group 1 included women with E-OP (n=16), Group 2 included women with L-OP (n=45), and Group 3 included women without preeclampsia (n=40).

resultsNo statistical differences were found in maternal age, body mass index, or number of gestations. Arginase levels were higher in Group 1 compared to Group 2 (p = 0.04) and Group 1 compared to Group 3 (p = 0.01). Total antioxidative capacity was higher in Group 1 compared to Group 2 (p = 0.03) and Group 1 compared to Group 3 (p = 0.001). Malondialdehyde levels were higher in Group 1 compared to Group 2 (p = 0.001) and Group 1 compared to Group 3 (p = 0.001). Total sulfhydryl compounds were lower in Group 1 compared to Group 2 (p = 0.01) and Group 1 compared to Group 3 (p = 0.001). No differences were observed between study groups in allostatic load markers.

conclusionsHigher levels of OS markers were found in women with E-OP compared to women with L-OP and controls.

Indexed as

allostatic loadarginaseearly-onset preeclampsialate-onset preeclampsiaoxidative stress

Identifiers

PMID39872579
PMCPMC11771531

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.