Evidence mapPaperPMID 39872756Full record

ReviewOpen access emergency medicine : OAEM2025

Peculiarities of in-Stent Thrombosis and Restenosis in Coronary Arteries Post-COVID-19: A Systematic Review of Clinical Cases and Case Series.

Lyudmila Pivina, Gulnara Batenova, Nazarbek Omarov, Diana Ygiyeva, Assylzhan Messova, Galiya Alibayeva, Ulzhan Jamedinova, Ruslan Kurumbayev, Maksim Pivin

Abstract readReview
In one paragraph

Review in Open access emergency medicine : OAEM, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lyudmila PivinaDepartment of Emergency Medicine, Semey Medical University, Semey, Abay Region, Kazakhstan.ORCID 0000-0002-8035-4866
Gulnara BatenovaDepartment of Emergency Medicine, Semey Medical University, Semey, Abay Region, Kazakhstan.ORCID 0000-0003-3198-1860
Nazarbek OmarovDepartment of Emergency Medicine, Semey Medical University, Semey, Abay Region, Kazakhstan.
Diana YgiyevaDepartment of Emergency Medicine, Semey Medical University, Semey, Abay Region, Kazakhstan.ORCID 0000-0001-8391-8842
Assylzhan MessovaDepartment of Emergency Medicine, Semey Medical University, Semey, Abay Region, Kazakhstan.
Galiya AlibayevaSemey Emergency Hospital, Semey, Abay Region, Kazakhstan.
Ulzhan JamedinovaDepartment of Emergency Medicine, Semey Medical University, Semey, Abay Region, Kazakhstan.
Ruslan KurumbayevDepartment of Emergency Medicine, Semey Medical University, Semey, Abay Region, Kazakhstan.
Maksim PivinNuclear Medicine Department, Center of Nuclear Medicine and Oncology, Semey, Abay Region, Kazakhstan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: One of the most serious complications of coronary artery stenting is restenosis and in-stent thrombosis; their prevalence can reach 20-25%. Stent thrombosis can be acute (up to 24 hours), subacute (24 hours to 30 days), late (30 days to 1 year), and very late (> 1 year after previous stenting). In the patients with COVID-19 in intensive care units, the proportion of those with elevated troponin levels reached 25%. Objective: Evaluation of the association between COVID-19 and the development of in-stent thrombosis and restenosis of the coronary arteries based on the analysis of clinical cases and case series. Materials and Methods: We searched the PubMed and Scopus databases for relevant case reports and case series of stent restenosis and in-stent thrombosis associated with coronavirus infection (CVI) published between 2020 and the present. Thirty-eight full-text publications were screened and manually checked for analysis. We found 10 publications describing cases of thrombosis and restenosis of stents associated with coronavirus infection, of which only 2 were case series. In total, we analyzed 22 cases. Results: In the structure of in-stent restenosis and thrombosis, 59.1% were very late, 9.1% were late; 18.2% were considered subacute events, and 13.6% were acute events. All cases were angiographically confirmed. The main location of restenosis or thrombosis was the left coronary artery (LAD) (51.1%), thrombosis of the right coronary artery (RCA) occurred in 27.3%, and location in circumflex artery was in 22.7%. All patients had COVID-19 confirmed by a PCR test or the presence of immunoglobulins G and M. In fourteen patients (54.5%), an X-ray examination showed the presence of bilateral polysegmental infiltration. Conclusion: Analysis of publications demonstrates the association between restenosis and in-stent thrombosis in patients with coronary arteries disease (CAD) and coronavirus infection.

Indexed as

case reportcase seriescoronary artery diseaseCOVID-19in-stent thrombosisrestenosisstenting

Identifiers

PMID39872756
PMCPMC11769847

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.