Evidence map›Paper›PMID 39872891›Full record

ArticleLife medicine2023

A biomarker framework for cardiac aging: the Aging Biomarker Consortium consensus statement.

Aging Biomarker Consortium, Weiwei Zhang, Yang Che, Xiaoqiang Tang, Siqi Chen, Moshi Song, Li Wang, Ai-Jun Sun, Hou-Zao Chen, Ming Xu and 19 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Targeting Arterial Dysfunction in Cardiovascular Disease Using Stem Cell-Based Therapies.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. An Expert Consensus Statement on Biomarkers of Aging for Use in Intervention Studies.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Aging Biomarker Consortium
Weiwei ZhangDepartment of Cardiology, The Second Medical Centre, Chinese PLA General Hospital, National Clinical Research Center for Geriatric Diseases, Beijing 100853, China.
Yang CheState Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
Xiaoqiang TangKey Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, State Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University, Chengdu 610041, China.ORCID https://orcid.org/0000-0003-1314-3417
Siqi ChenState Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Moshi SongState Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Li WangState Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.ORCID https://orcid.org/0000-0002-5570-1336
Ai-Jun SunDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai 200433, China.
Hou-Zao ChenDepartment of Biochemistry and Molecular Biology, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China.ORCID https://orcid.org/0000-0001-6805-3182
Ming XuDepartment of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, Beijing 100191, China.
Miao WangState Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
Jun PuState Key Laboratory for Oncogenes and Related Genes, Department of Cardiology, Shanghai Jiao Tong University, Shanghai 200025, China.ORCID https://orcid.org/0000-0003-2240-5108
Zijian LiDepartment of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, Beijing 100191, China.
Junjie XiaoShanghai Engineering Research Center of Organ Repair, School of Medicine, Shanghai University, Shanghai 200444, China.
Chun-Mei CaoLaboratory of Cardiovascular Science, Beijing Clinical Research Institute, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.ORCID https://orcid.org/0000-0002-7162-3104
Yan ZhangState Key Laboratory of Membrane Biology, Institute of Molecular Medicine, College of Future Technology, Peking University, Beijing 100871, China.
Yao LuClinical Research Center, The Third Xiangya Hospital, Central South University, Changsha 410013, China.ORCID https://orcid.org/0000-0001-6743-7870
Yingxin ZhaoDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing 100029, China.
Yan-Jiang WangDepartment of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Third Military Medical University, Chongqing 400042, China.
Cuntai ZhangGerontology Center of Hubei Province, Wuhan 430000, China.
Tao ShenThe Key Laboratory of Geriatrics, Beijing Institute of Geriatrics, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Hospital/National Center of Gerontology of National Health Commission, Beijing 100730, China.ORCID https://orcid.org/0000-0001-5856-0818
Weiqi ZhangUniversity of Chinese Academy of Sciences, Beijing 100049, China.
Ling TaoDepartment of Cardiology, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032, China.ORCID https://orcid.org/0000-0002-7076-1185
Jing QuUniversity of Chinese Academy of Sciences, Beijing 100049, China.
Yi-Da TangDepartment of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, Key Laboratory of Molecular Cardiovascular Sciences (Peking University), Ministry of Education, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Key Laboratory of Cardiovascular Receptors Research, Beijing 100191, China.ORCID https://orcid.org/0000-0002-9712-803X
Guang-Hui LiuState Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.ORCID https://orcid.org/0000-0001-9289-8177
Gang PeiShanghai Key Laboratory of Signaling and Disease Research, Laboratory of Receptor-Based Biomedicine, The Collaborative Innovation Center for Brain Science, School of Life Sciences and Technology, Tongji University, Shanghai 200070, China.
Jian LiThe Key Laboratory of Geriatrics, Beijing Institute of Geriatrics, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Hospital/National Center of Gerontology of National Health Commission, Beijing 100730, China.ORCID https://orcid.org/0000-0003-3320-7924
Feng CaoDepartment of Cardiology, The Second Medical Centre, Chinese PLA General Hospital, National Clinical Research Center for Geriatric Diseases, Beijing 100853, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac aging constitutes a significant risk factor for cardiovascular diseases prevalent among the elderly population. Urgent attention is required to prioritize preventive and management strategies for age-related cardiovascular conditions to safeguard the well-being of elderly individuals. In response to this critical challenge, the Aging Biomarker Consortium (ABC) of China has formulated an expert consensus on cardiac aging biomarkers. This consensus draws upon the latest scientific literature and clinical expertise to provide a comprehensive assessment of biomarkers associated with cardiac aging. Furthermore, it presents a standardized methodology for characterizing biomarkers across three dimensions: functional, structural, and humoral. The functional dimension encompasses a broad spectrum of markers that reflect diastolic and systolic functions, sinus node pacing, neuroendocrine secretion, coronary microcirculation, and cardiac metabolism. The structural domain emphasizes imaging markers relevant to concentric cardiac remodeling, coronary artery calcification, and epicardial fat deposition. The humoral aspect underscores various systemic (

Identifiers

PMID39872891
PMCPMC11749273

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.