Evidence mapPaperPMID 39872930Full record

ReviewBiomaterials translational2024

Future perspectives: advances in bone/cartilage organoid technology and clinical potential.

Jingtao Huang, Aikang Li, Rongji Liang, Xiaohao Wu, Shicheng Jia, Jiayou Chen, Zilu Jiao, Canfeng Li, Xintao Zhang, Jianjing Lin

Abstract readReview
In one paragraph

Review in Biomaterials translational, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
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  7. Review
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jingtao HuangDepartment of Sports Medicine and Rehabilitation, Peking University Shenzhen Hospital, Shenzhen, Gunagdong Province, China.
Aikang LiDepartment of Clinical Medicine, Shantou University Medical College, Shantou, Gunagdong Province, China.
Rongji LiangDepartment of Sports Medicine and Rehabilitation, Peking University Shenzhen Hospital, Shenzhen, Gunagdong Province, China.
Xiaohao WuImmunology and Rheumatology, School of Medicine, Stanford University, Palo Alto, CA, USA.
Shicheng JiaDepartment of Sports Medicine and Rehabilitation, Peking University Shenzhen Hospital, Shenzhen, Gunagdong Province, China.
Jiayou ChenDepartment of Sports Medicine and Rehabilitation, Peking University Shenzhen Hospital, Shenzhen, Gunagdong Province, China.
Zilu JiaoDepartment of Sports Medicine and Rehabilitation, Peking University Shenzhen Hospital, Shenzhen, Gunagdong Province, China.
Canfeng LiDepartment of Sports Medicine and Rehabilitation, Peking University Shenzhen Hospital, Shenzhen, Gunagdong Province, China.
Xintao ZhangDepartment of Sports Medicine and Rehabilitation, Peking University Shenzhen Hospital, Shenzhen, Gunagdong Province, China.
Jianjing LinDepartment of Sports Medicine and Rehabilitation, Peking University Shenzhen Hospital, Shenzhen, Gunagdong Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone and cartilage tissues are essential for movement and structure, yet diseases like osteoarthritis affect millions. Traditional therapies have limitations, necessitating innovative approaches. Organoid technology, leveraging stem cells' regenerative potential, offers a novel platform for disease modelling and therapy. This review focuses on advancements in bone/cartilage organoid technology, highlighting the role of stem cells, biomaterials, and external factors in organoid development. We discuss the implications of these organoids for regenerative medicine, disease research, and personalised treatment strategies, presenting organoids as a promising avenue for enhancing cartilage repair and bone regeneration. Bone/cartilage organoids will play a greater role in the treatment of bone/cartilage diseases in the future, and promote the progress of biological tissue engineering.

Indexed as

biomaterialsbonecartilageorganoidsstem cellstissue engineering

Identifiers

PMID39872930
PMCPMC11764185

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.