ArticleJournal of dental sciences2025
Antimicrobial properties of bimetallic-containing mesoporous bioglass against
Article in Journal of dental sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Mesoporous Bioactive Glass: Preparation, Characterisation, and Emerging Applications in Regenerative Medicine and Dentistry.International dental journal · 2026Review
- Insights on Immobilization of Cd Contamination in Soil: Synergic Impacts of Water Management and Bauxite Residue.ACS omega · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/purpose: Various pulp-covering materials offer advantages in regenerative root canal treatment, but each has limitations, highlighting the need for more effective antibacterial strategies for pulp repair and regeneration. Mesoporous bioactive glasses (MBG) show significant biological activity, making them valuable in tissue/dental repair. Silver-incorporated MBG exhibits promising antibacterial effects against various bacteria; copper ions are crucial in regulating angiogenesis signals. Co-loading copper and silver in bioactive glasses has been explored to address clinical challenges. This study modified the preparation of silver-copper bimetallic mesoporous bioactive glass, analyzing their textural properties and antibacterial activity against Materials and methods: The silver-copper co-loaded bioactive glass (designated as AgCu/80S) was synthesized using a sol-gel technique with modifications. Textural analyses were carried out via X-ray diffraction, UV-Vis spectroscopy, Brunauer-Emmett-Teller analysis, and transmission electron microscope. The ion-releasing activity determined using inductively coupled plasma-mass spectrometry, and the antibacterial activity against Results: The modification led to weaker crystallization of calcium silicate, altering ion-releasing and antibacterial activities. Ag3Cu2/80S exhibited the highest released silver ion concentration at 112.6 ppm, with an inhibition zone of 9.09 ± 0.09 mm in disk diffusion assays. However, the inhibition zone of Ag2Cu3/80S was 9.92 ± 0.04 mm, implying that the antibacterial activity may not only be influenced by silver ions. Conclusion: The AgCu/80S showed a potential antibacterial activity against
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.