Evidence map›Paper›PMID 39873589›Full record

ArticleGenetics and molecular biology2025

A variant W chromosome in Centromochlus heckelii (Siluriformes, Auchenipteridae) and the role of repeated DNA in its heteromorphism.

Chrystian Aparecido Grillo Haerter, Patrik Ferreira Viana, Fábio Hiroshi Takagui, Sandro Tonello, Vladimir Pavan Margarido, Daniel Rodrigues Blanco, Josiane Baccarin Traldi, Roberto Laridondo Lui, Eliana Feldberg

Abstract read
In one paragraph

Article in Genetics and molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Satellite DNA Genomics: The Ongoing Story.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chrystian Aparecido Grillo HaerterInstituto Nacional de Pesquisas da Amazônia, Programa de Pós-Graduação em Genética, Conservação e Biologia Evolutiva (PPG GCBEv), Manaus, AM, Brazil.ORCID http://orcid.org/0000-0002-8772-978X
Patrik Ferreira VianaInstituto Nacional de Pesquisas da Amazônia, Programa de Pós-Graduação em Genética, Conservação e Biologia Evolutiva (PPG GCBEv), Manaus, AM, Brazil.ORCID http://orcid.org/0000-0002-8172-0725
Fábio Hiroshi TakaguiInstituto Nacional de Pesquisas da Amazônia, Programa de Pós-Graduação em Genética, Conservação e Biologia Evolutiva (PPG GCBEv), Manaus, AM, Brazil.ORCID http://orcid.org/0000-0002-6963-9473
Sandro TonelloInstituto Nacional de Pesquisas da Amazônia, Programa de Pós-Graduação em Genética, Conservação e Biologia Evolutiva (PPG GCBEv), Manaus, AM, Brazil.ORCID http://orcid.org/0000-0002-7213-8717
Vladimir Pavan MargaridoUniversidade Estadual do Oeste do Paraná, Centro de Ciências Biológicas e da Saúde (CCBS), Cascavel, PR, Brazil.ORCID http://orcid.org/0000-0002-0823-6646
Daniel Rodrigues BlancoUniversidade Tecnológica Federal do Paraná, Coordenação de Ciências Biológicas (COBIO), Campus Santa Helena, Paraná, PR, Brazil.ORCID http://orcid.org/0000-0003-1619-2417
Josiane Baccarin TraldiUniversidade Tecnológica Federal do Paraná, Coordenação de Ciências Biológicas (COBIO), Campus Santa Helena, Paraná, PR, Brazil.ORCID http://orcid.org/0000-0003-3019-7441
Roberto Laridondo LuiUniversidade Estadual do Oeste do Paraná, Centro de Ciências Biológicas e da Saúde (CCBS), Cascavel, PR, Brazil.ORCID http://orcid.org/0000-0003-4310-4865
Eliana FeldbergInstituto Nacional de Pesquisas da Amazônia, Programa de Pós-Graduação em Genética, Conservação e Biologia Evolutiva (PPG GCBEv), Manaus, AM, Brazil.ORCID http://orcid.org/0000-0002-2962-4541

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Centromochlus heckelii has the lowest diploid chromosome number (2n = 46) and the only described heteromorphic sex chromosome system in Auchenipteridae. This study presents a population of C. heckelii from the Central Amazon basin with subtle variations in the karyotype composition and a variant W chromosome with distinct morphology and increased C-positive heterochromatin content. In this population, the W chromosome is subtelocentric, whereas the only previous study on C. heckelii reported a metacentric W chromosome. Constitutive heterochromatin (CH) and accumulation of microsatellite motifs have significantly contributed to this W chromosome enlargement. Notably, this population exhibits numerous interstitial telomeric sites (ITSs). Some of these ITSs might represent genuine chromosomal fusion points due to the reduced 2n; however, additional mechanisms, such as chromosomal inversions, translocations, transpositions, or association with satellite DNA, are likely responsible for this unusual pattern. The 18S rDNA sites were found in both the Z and W chromosomes of all individuals. However, two individuals exhibited an additional 18S rDNA site in a single homologous of the chromosome pair 20, characterizing an intrapopulation polymorphism. The 5S rDNA sites were found in two chromosome pairs, distinguishing this population from other Centromochlinae species and further supporting it as one of the most efficient cytotaxonomic markers within the subfamily.

Identifiers

PMID39873589
PMCPMC11789463

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.