Evidence map›Paper›PMID 39874079›Full record

ArticleTherapeutic delivery2025

Development of propranolol loaded SLN for transdermal delivery:

Eskandar Moghimipour, Mohammadamin Khazali, Behzad Sharif MakhmalZadeh, Maryam Abedini Baghbadorani, Ali Zangeneh, Somayeh Sohrabi, Fereshteh Nejaddehbashi, Fatemeh Hajipour, Somayeh Handali

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Article in Therapeutic delivery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Eskandar MoghimipourNanotechnology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Mohammadamin KhazaliNanotechnology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Behzad Sharif MakhmalZadehNanotechnology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Maryam Abedini BaghbadoraniDepartment of Toxicology, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Ali ZangenehNanotechnology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Somayeh SohrabiMechanical Engineering Department, Sharif University of Technology, Tehran, Iran.
Fereshteh NejaddehbashiCellular and Molecular Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Fatemeh HajipourDepartment of Medicinal Chemistry, Faculty of pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Somayeh HandaliMedical Biomaterials Research Center (MBRC), Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe study aimed to formulate solid lipid nanoparticles (SLNs) for the transdermal delivery of PPL to improve skin retention and efficacy. MATERIALS AND

methodThe particle size distribution of SLNs was determined and the morphology of SLNs was also analyzed by SEM.

resultsThe results indicated successful encapsulation of PPL in SLNs (59.38%), which exhibited a spherical shape and smooth surface. Compared to PPL solution, SLNs demonstrated a prolonged drug release profile

conclusionTo the best of our knowledge, this is the first study that indicates SLNs can be considered as a promising nanocarriers for transdermal delivery of PPL.

Indexed as

LiposomesNanoparticle Drug Delivery SystemNanoparticlesPropranololAdministration, CutaneousAnimalsCell SurvivalComputer SimulationDrug LiberationDrug StabilityHEK293 CellsHumansMaleParticle SizeRatsRats, WistarLipid NanoparticlesLiposomesNanoparticle Drug Delivery SystemPropranololdrug retentionpropranololskinSLNtransdermal delivery

Identifiers

PMID39874079
PMCPMC11875500

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.