Evidence map›Paper›PMID 39875366›Full record

ArticleTranslational psychiatry2025

Nitrous oxide exerts rewarding effect via regulating D1 receptor and BDNF pathway in ventral tegmental area-nucleus accumbens dopamine circuit.

Wen-Qi Li, Sheng-Nan Liu, Si-Chang Yang, Xiang Lin, Zhang-Jin Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wen-Qi Li *School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID http://orcid.org/0009-0001-8388-9612
Sheng-Nan Liu *School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID http://orcid.org/0000-0003-2236-7914
Si-Chang YangSchool of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID http://orcid.org/0000-0003-2942-7238
Xiang LinSchool of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China. linxiang@hku.hk.ORCID http://orcid.org/0000-0002-9065-2744
Zhang-Jin ZhangSchool of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China. zhangzj@hku.hk.ORCID http://orcid.org/0000-0002-8416-3426

Funding

Food and Health Bureau of the Government of the Hong Kong Special Administrative Region | Health and Medical Research Fund (HMRF) 12133711Research Grants Council, University Grants Committee (RGC, UGC) 17115017
6 · The paper itself

Abstract

Recreational use of nitrous oxide (N

Indexed as

Brain-Derived Neurotrophic FactorNitrous OxideNucleus AccumbensReceptors, Dopamine D1RewardVentral Tegmental AreaAnimalsBenzazepinesDopamineDopamine AntagonistsHaloperidolMaleMiceMice, Inbred C57BLSignal TransductionBdnf protein, mouseBenzazepinesBrain-Derived Neurotrophic FactorDopamineDopamine AntagonistsDrd1 protein, mouseHaloperidolNitrous OxideReceptors, Dopamine D1SCH 23390

Identifiers

PMID39875366
PMCPMC11775255

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.