Evidence map›Paper›PMID 39875719›Full record

SynthesisJournal of assisted reproduction and genetics2025

Effects of emotions on IVF/ICSI outcomes in infertile women: a systematic review and meta-analysis.

Qianqian Lu, Yun Cheng, Zhi Zhou, Jianing Fan, Jie Chen, Chen Yan, Xin Zeng, Juan Yang, Xinyan Wang

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of assisted reproduction and genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qianqian Lu *Women's Hospital of Nanjing Medical University, Nanjing Women and Children's Healthcare Hospital, Nanjing Women and Children's Healthcare Institute, Nanjing, Jiangsu, China.
Yun Cheng *Women's Hospital of Nanjing Medical University, Nanjing Women and Children's Healthcare Hospital, Nanjing Women and Children's Healthcare Institute, Nanjing, Jiangsu, China.
Zhi ZhouReproductive Medical Center, Hainan Women and Children's Medical Center, Haikou, Hainan, China.
Jianing FanWomen's Hospital of Nanjing Medical University, Nanjing Women and Children's Healthcare Hospital, Nanjing Women and Children's Healthcare Institute, Nanjing, Jiangsu, China.
Jie ChenWomen's Hospital of Nanjing Medical University, Nanjing Women and Children's Healthcare Hospital, Nanjing Women and Children's Healthcare Institute, Nanjing, Jiangsu, China.
Chen YanWomen's Hospital of Nanjing Medical University, Nanjing Women and Children's Healthcare Hospital, Nanjing Women and Children's Healthcare Institute, Nanjing, Jiangsu, China.
Xin ZengWomen's Hospital of Nanjing Medical University, Nanjing Women and Children's Healthcare Hospital, Nanjing Women and Children's Healthcare Institute, Nanjing, Jiangsu, China.
Juan YangAffiliated Maternal and Child Health Care Center, Hainan Medical University, Hainan Academy of Medical Sciences, Haikou, Hainan, China. hy0203091@muhn.edu.cn.
Xinyan WangWomen's Hospital of Nanjing Medical University, Nanjing Women and Children's Healthcare Hospital, Nanjing Women and Children's Healthcare Institute, Nanjing, Jiangsu, China. maymay0512@njmu.edu.cn.ORCID http://orcid.org/0000-0001-5428-4916

Funding

Hainan Provincial Natural Science Foundation of China 822RC714Jiangsu Provincial Key Research and Development Program BE2021613Science and Technology Department of Hainan Province ZDYF2022SHFZ280
6 · The paper itself

Abstract

To assess whether infertile women's psychological conditions, such as depression, anxiety, and stress, are associated with in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) outcomes, we systematically searched for relevant articles from January 1, 2004, to March 29, 2024, in five databases, including PubMed, Web of Science, EMBASE, Cochrane Library, and PsycINFO. A random-effects model was used to examine pooled standardized mean differences (SMD) and 95% confidence interval (CI). A total of 29 articles fulfilled the inclusion criteria and were included in this meta-analysis. The statistical analysis revealed that infertile women with higher levels of anxiety [SMD: -0.17, 95% CI: (-0.27, -0.06), P = 0.002] and depression [SMD: -0.17, 95% CI: (-0.30, -0.04), P = 0.008] were less likely to have a successful pregnancy following IVF/ICSI treatment. Although not statistically significant, the results indicate a trend of increasing IVF/ICSI success with increasing participants' perceived stress levels [SMD: 0.09, 95% CI: (-0.01, 0.19), P = 0.07]. There was also no statistically significant correlation between infertility-related stress and IVF/ICSI outcomes [SMD: -0.26, 95% CI: (-0.79, 0.28), P = 0.35]. In general, it suggested that medical personnel should be aware of the mental health of infertile women involved in IVF/ICSI.

Indexed as

EmotionsFertilization in VitroInfertility, FemaleSperm Injections, IntracytoplasmicAnxietyDepressionFemaleHumansPregnancyPregnancy RateStress, PsychologicalAnxietyDepressionInfertility-related stressIntracytoplasmic sperm injectionIn vitro fertilizationStress

Identifiers

PMID39875719
PMCPMC12055742

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.