Evidence map›Paper›PMID 39876576›Full record

ReviewAging cell2025

Raman Spectroscopy in Cellular and Tissue Aging Research.

Jeong Hee Kim, Daejong Yang, Seungman Park

Abstract readReview
In one paragraph

Review in Aging cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jeong Hee KimDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0001-5689-1445
Daejong YangDepartment of Mechanical and Automotive Engineering, Kongju National University, Cheonan, Republic of Korea.
Seungman ParkDepartment of Mechanical Engineering, University of Nevada, Las Vegas, Las Vegas, Nevada, USA.ORCID 0000-0001-7275-8345

Funding

Characterization of relation between tissue viscoelasticity and tumor progression in aging tissuesK25AG070286 · NIA · UNIVERSITY OF NEVADA LAS VEGAS · PI PARK, SEUNGMAN · 2021 to 2025
$734k
National Institute on Aging (NIA) K25AG070286NIA NIH HHS K25 AG070286
6 · The paper itself

Abstract

The establishment of various molecular, physiological, and genetic markers for cellular senescence and aging-associated conditions has progressed the aging study. To identify such markers, a combination of optical, proteomic-, and sequencing-based tools is primarily used, often accompanying extrinsic labels. Yet, the tools for clinical detection at the molecular, cellular, and tissue levels are still lacking which profoundly hinders advancements in the specific detection and timely prevention of aging-related diseases and pathologies. Raman spectroscopy, with its capability for rapid, label-free, and non-invasive analysis of molecular compositions and alterations in aging cells and tissues, holds considerable promise for in vivo applications. In this review, we present recent advancements in the application of Raman spectroscopy to the study of aging in cells and tissues. We explore the use of Raman spectroscopy and related techniques for detecting cellular aging and senescence, focusing on the molecular alterations that accompany these processes. Subsequently, we provide a review of the application of Raman spectroscopy in identifying aging-related changes in various molecules within tissues and organs.

Indexed as

AgingCellular SenescenceSpectrum Analysis, RamanAnimalsHumansagingcellRaman spectroscopysenescencetissue

Identifiers

PMID39876576
PMCPMC11822629

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.