Evidence mapPaperPMID 39876965Full record

ArticleArchives of endocrinology and metabolism2024

Circulating endothelial progenitor cells and inflammatory markers in type 1 diabetes after an acute session of aerobic exercise.

Patrícia Martins Bock, Raíssa Borges Monteiro, Clara Krummenauer Maraschin, Ana Paula Alegretti, Mariela Granero Farias, Fabiane Spagnol, Patricia Luciana da Costa Lopez, Lucas Porto Santos, Lucas Helal, Ruy Silveira Moraes and 2 more

Abstract read
In one paragraph

Article in Archives of endocrinology and metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Patrícia Martins BockInstituto Nacional de Ciência e Tecnologia para Avaliação de Tecnologias em Saúde Hospital de Clínicas de Porto Alegre Porto AlegreRS Brasil Instituto Nacional de Ciência e Tecnologia para Avaliação de Tecnologias em Saúde (IATS) - CNPq/Brasil, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brasil.ORCID https://orcid.org/0000-0001-8572-3950
Raíssa Borges MonteiroCentro de Pesquisa Clínica/Centro de Pesquisa Experimental Hospital de Clínicas de Porto Alegre Porto AlegreRS Brasil Centro de Pesquisa Clínica/Centro de Pesquisa Experimental, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brasil.ORCID https://orcid.org/0000-0003-4920-8112
Clara Krummenauer MaraschinUniversidade Federal do Rio Grande do Sul Faculdade de Medicina Departamento de Clínica Médica Porto AlegreRS Brasil Universidade Federal do Rio Grande do Sul, Faculdade de Medicina, Departamento de Clínica Médica, Programa de Pós-graduação em Ciências Médicas: Endocrinologia, Porto Alegre, RS, Brasil.ORCID https://orcid.org/0000-0003-1728-8103
Ana Paula AlegrettiServiço de Diagnóstico Laboratorial Hospital de Clínicas de Porto Alegre Porto AlegreRS Brasil Serviço de Diagnóstico Laboratorial (SDLab), Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brasil.ORCID https://orcid.org/0000-0002-8444-4359
Mariela Granero FariasServiço de Diagnóstico Laboratorial Hospital de Clínicas de Porto Alegre Porto AlegreRS Brasil Serviço de Diagnóstico Laboratorial (SDLab), Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brasil.ORCID https://orcid.org/0000-0002-4502-9312
Fabiane SpagnolServiço de Diagnóstico Laboratorial Hospital de Clínicas de Porto Alegre Porto AlegreRS Brasil Serviço de Diagnóstico Laboratorial (SDLab), Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brasil.ORCID https://orcid.org/0000-0001-7669-2902
Patricia Luciana da Costa LopezCentro de Pesquisa Clínica/Centro de Pesquisa Experimental Hospital de Clínicas de Porto Alegre Porto AlegreRS Brasil Centro de Pesquisa Clínica/Centro de Pesquisa Experimental, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brasil.ORCID https://orcid.org/0000-0002-0375-9181
Lucas Porto SantosUniversidade Federal do Rio Grande do Sul Porto AlegreRS Brasil Universidade Federal do Rio Grande do Sul, Programa de Pós-graduação em Ciências da Saúde: Cardiologia, Porto Alegre, RS, Brasil.ORCID https://orcid.org/0000-0001-7934-0427
Lucas HelalUniversidade Federal do Rio Grande do Sul Porto AlegreRS Brasil Universidade Federal do Rio Grande do Sul, Programa de Pós-graduação em Ciências da Saúde: Cardiologia, Porto Alegre, RS, Brasil.ORCID https://orcid.org/0000-0002-6900-7185
Ruy Silveira MoraesCentro de Pesquisa Clínica/Centro de Pesquisa Experimental Hospital de Clínicas de Porto Alegre Porto AlegreRS Brasil Centro de Pesquisa Clínica/Centro de Pesquisa Experimental, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brasil.ORCID https://orcid.org/0000-0001-6802-7128
Daniel UmpierreInstituto Nacional de Ciência e Tecnologia para Avaliação de Tecnologias em Saúde Hospital de Clínicas de Porto Alegre Porto AlegreRS Brasil Instituto Nacional de Ciência e Tecnologia para Avaliação de Tecnologias em Saúde (IATS) - CNPq/Brasil, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brasil.ORCID https://orcid.org/0000-0001-6953-0163
Beatriz D SchaanInstituto Nacional de Ciência e Tecnologia para Avaliação de Tecnologias em Saúde Hospital de Clínicas de Porto Alegre Porto AlegreRS Brasil Instituto Nacional de Ciência e Tecnologia para Avaliação de Tecnologias em Saúde (IATS) - CNPq/Brasil, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brasil.ORCID https://orcid.org/0000-0002-2128-8387

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To determine circulating endothelial progenitor cells (EPC) counts and levels of inflammatory markers in individuals with and without type 1 diabetes mellitus (T1DM) in response to an intense aerobic exercise session. Subjects and methods: In total, 15 adult men with T1DM and 15 healthy individuals underwent a 30-minute aerobic exercise session on a cycle ergometer at 60% of the peak heart rate. The EPC count (CD45 Results: We found no difference within or between groups regarding EPC counts before and after the aerobic exercise: healthy individuals, 0.02% change (95% confidence interval [CI] -0.04%-0.08%); individuals with T1DM, 0.00% (95%CI -0.01%-0.01%). We also found no difference in TNF-α levels before and after exercise in healthy individuals (210.2, interquartile range [IQR] 142.1-401.2 pg/mL and 191.3, IQR 136.4-350.5 pg/mL, respectively) and in patients with T1DM (463.8, IQR 201.4-4306.0 pg/mL and 482.7, IQR 143.8-4304.3 pg/mL, respectively). Similarly, no difference in IL-6 levels was observed before and after exercise in healthy individuals (148.2, IQR 147.5-148.6 pg/mL and 148.2, IQR 147.7-148.6 pg/mL, respectively) and individuals with T1DM (147.2, IQR 145.9-147.7 pg/mL and 147.2, IQR 146.8-147.8 pg/mL, respectively). Conclusions: Patients with T1DM and healthy controls had comparable EPC responses to aerobic exercise, most likely due to the absence of a chronic inflammatory state.

Indexed as

Diabetes Mellitus, Type 1Endothelial Progenitor CellsExerciseAdultBiomarkersCase-Control StudiesHumansInflammationInterleukin-6MaleTumor Necrosis Factor-alphaYoung AdultBiomarkersInterleukin-6Tumor Necrosis Factor-alphachemokine receptorsendotheliuminterleukin 6Tumor necrosis factor-alpha

Identifiers

PMID39876965
PMCPMC11771752

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.