ArticleCurrent physical medicine and rehabilitation reports2021
Preliminary evidence on the effects of exercise on tumor biology: a potential guide for prescribing exercise.
Article in Current physical medicine and rehabilitation reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Patient stratification in exercise oncology: matching exercise modalities to immune phenotypes to optimize immunotherapy response.Translational oncology · 2026Review
- Exercise interventions remodel the aging microenvironment to improve prognosis in older patients with cancer.Frontiers in immunology · 2026Review
- The multidimensional roles and mechanisms of exercise intervention in pediatric oncology.Frontiers in immunology · 2026Review
- The Influence of an Acute Endurance Intervention on Breast Cancer Cell Growth-A Pilot Study.International journal of molecular sciences · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Purpose of review: This report reviews the preliminary evidence of how exercise may alter the tumor microenvironment and tumor biology in animal and human studies; and how to incorporate this information in clinical practice of oncology rehabilitation. Recent findings: Potential mechanisms explaining the impact of exercise on the tumor microenvironment include activating and mobilizing immune cells, reducing inflammation, and modifying tumor vasculature which enhances the delivery of anticancer therapies. Pre-clinical data translates to promising preliminary data in human studies; however, randomized, controlled trials in patients are limited. Summary: Despite the paucity of robust data demonstrating the beneficial effects of exercise on tumor biology, the strong observational and epidemiological data and limited interventional trials encourage the continued prescribing of exercise by rehabilitation professionals for cancer survivors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.