Evidence map›Paper›PMID 39879164›Full record

ArticlePloS one2025

Evaluation of anti-inflammatory and wound healing properties of Tinospora cordifolia extract.

Shohag Chandra Das, Subrato Biswas, Olin Khan, Rupa Akter, Md Abul Kalam Azad, Sujan Kumar Sarkar, Md Abdul Masum, Sultana Bedoura

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shohag Chandra DasDepartment of Dyes and Chemical Engineering, Bangladesh University of Textiles, Dhaka, Bangladesh.
Subrato BiswasDepartment of Anatomy, Histology & Physiology, Sher-e-Bangla Agricultural University, Dhaka, Bangladesh.
Olin KhanDepartment of Wet Process Engineering, Bangladesh University of Textiles, Dhaka, Bangladesh.
Rupa AkterDepartment of Anatomy, Histology & Physiology, Sher-e-Bangla Agricultural University, Dhaka, Bangladesh.
Md Abul Kalam AzadDepartment of Dyes and Chemical Engineering, Bangladesh University of Textiles, Dhaka, Bangladesh.
Sujan Kumar SarkarDepartment of Anatomy, Histology & Physiology, Sher-e-Bangla Agricultural University, Dhaka, Bangladesh.
Md Abdul MasumDepartment of Anatomy, Histology & Physiology, Sher-e-Bangla Agricultural University, Dhaka, Bangladesh.
Sultana BedouraDepartment of Dyes and Chemical Engineering, Bangladesh University of Textiles, Dhaka, Bangladesh.ORCID 0000-0002-5318-0557

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tinospora cordifolia extract exhibits diverse benefits-anti-arthritis, anti-malarial, anti-allergic, anti-diabetic, antihepatotoxic, and antipyretic effects. Its specific anti-inflammatory and healing capacities remain unexplored, prompting a study utilizing a mouse skin wound model and direct T. cordifolia extraction. UV-Vis spectroscopy depicted an absorption range of 200-400 nm, while FTIR analysis identified alcohols, phenols, amines, amides, aldehydes, ketones, alkanes, and alkenes. GC-MS analysis revealed the presence of components: 5methyl-5-Hexen-2-Ol, n-hexadecenoic acid, cholesta-4,6-dien-3beta-ol, stigmasterol, β-sitosterol, stearate which are present in the extract. Histopathological examination confirmed accelerated wound healing, showcasing reduced inflammation, restored blood vessels, collagen fibers, and swift epidermal closure. T. cordifolia extract exhibits promise in enhancing wound healing through its antibacterial, anti-inflammatory properties.

Indexed as

Anti-Inflammatory AgentsPlant ExtractsTinosporaWound HealingAnimalsMaleMiceSkinAnti-Inflammatory AgentsPlant Extracts

Identifiers

PMID39879164
PMCPMC11778766

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.