Evidence map›Paper›PMID 39879235›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

The chloroplast RNA-binding protein CP29A supports

Benjamin Lenzen, Florian Rösch, Julia Legen, Hannes Ruwe, Nitin Kachariya, Michael Sattler, Ian Small, Christian Schmitz-Linneweber

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Benjamin Lenzen *Molecular Genetics, Institute of Biology, Faculty of Life Sciences, Humboldt Universität zu Berlin, Berlin 10115, Germany.ORCID 0000-0002-7881-9513
Florian Rösch *Molecular Genetics, Institute of Biology, Faculty of Life Sciences, Humboldt Universität zu Berlin, Berlin 10115, Germany.
Julia LegenMolecular Genetics, Institute of Biology, Faculty of Life Sciences, Humboldt Universität zu Berlin, Berlin 10115, Germany.ORCID 0009-0003-5868-381X
Hannes RuweMolecular Genetics, Institute of Biology, Faculty of Life Sciences, Humboldt Universität zu Berlin, Berlin 10115, Germany.ORCID 0000-0002-5576-5807
Nitin KachariyaMolecular Targets and Therapeutics Center, Helmholtz Munich, Institute of Structural Biology, Neuherberg 85764, Germany.ORCID 0000-0002-0839-3668
Michael SattlerMolecular Targets and Therapeutics Center, Helmholtz Munich, Institute of Structural Biology, Neuherberg 85764, Germany.
Ian SmallAustralian Research Council Centre of Excellence in Plant Energy Biology, School of Molecular Sciences, The University of Western Australia, Perth, WA 6009, Australia.
Christian Schmitz-LinneweberMolecular Genetics, Institute of Biology, Faculty of Life Sciences, Humboldt Universität zu Berlin, Berlin 10115, Germany.ORCID 0000-0002-6125-4253

Funding

Deutsche Forschungsgemeinschaft (DFG) SPP1935Deutsche Forschungsgemeinschaft (DFG) SPP2191Deutsche Forschungsgemeinschaft (DFG) TRR175-A02
6 · The paper itself

Abstract

The chloroplast genome encodes key components of the photosynthetic light reaction machinery as well as the large subunit of the enzyme central for carbon fixation, Ribulose-1,5-bisphosphat-carboxylase/-oxygenase (RuBisCo). Its expression is predominantly regulated posttranscriptionally, with nuclear-encoded RNA-binding proteins (RBPs) playing a key role. Mutants of chloroplast gene expression factors often exhibit impaired chloroplast biogenesis, especially in cold conditions. Low temperatures pose a challenge for plants as this leads to electron imbalances and oxidative damage. A well-known response of plants to this problem is to increase the production of RuBisCo and other Calvin Cycle enzymes in the cold, but how this is achieved is unclear. The chloroplast RBP CP29A has been shown to be essential for cold resistance in growing leaf tissue of

Indexed as

AcclimatizationArabidopsisArabidopsis ProteinsChloroplast ProteinsChloroplastsRibulose-Bisphosphate CarboxylaseRNA-Binding Proteins5' Untranslated RegionsCold TemperatureGene Expression Regulation, PlantPhotosynthesis5' Untranslated RegionsArabidopsis ProteinsChloroplast ProteinsRbcL protein, plastidRibulose-Bisphosphate CarboxylaseRNA-Binding ProteinschloroplastCLIPcold acclimationRNA bindingRuBisCo

Identifiers

PMID39879235
PMCPMC11804644

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.