Evidence map›Paper›PMID 39881074›Full record

Trial reportBreast cancer research and treatment2025

Triaging mammography with artificial intelligence: an implementation study.

Sarah M Friedewald, Marcin Sieniek, Sunny Jansen, Fereshteh Mahvar, Timo Kohlberger, David Schacht, Sonya Bhole, Dipti Gupta, Shruthi Prabhakara, Scott Mayer McKinney and 20 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Breast cancer research and treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Balancing between A and I.Acta oncologica (Stockholm, Sweden) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Sarah M Friedewald *Feinberg School of Medicine, Northwestern University, 420 E Superior St, Chicago, IL, 60611, USA. sarah.friedewald@nm.org.ORCID https://orcid.org/0000-0002-9623-7533
Marcin Sieniek *Google Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0000-0003-3916-3205
Sunny Jansen *Google Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0009-0003-4957-4486
Fereshteh MahvarGoogle Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0009-0009-6463-0451
Timo KohlbergerGoogle Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0009-0003-7145-6128
David SchachtFeinberg School of Medicine, Northwestern University, 420 E Superior St, Chicago, IL, 60611, USA.ORCID https://orcid.org/0009-0000-9046-9811
Sonya BholeFeinberg School of Medicine, Northwestern University, 420 E Superior St, Chicago, IL, 60611, USA.ORCID https://orcid.org/0000-0002-0625-9211
Dipti GuptaFeinberg School of Medicine, Northwestern University, 420 E Superior St, Chicago, IL, 60611, USA.ORCID https://orcid.org/0000-0003-4889-3357
Shruthi PrabhakaraGoogle Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0000-0002-9489-7415
Scott Mayer McKinneyGoogle Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0000-0003-0707-7169
Stacey CaronFeinberg School of Medicine, Northwestern University, 420 E Superior St, Chicago, IL, 60611, USA.ORCID https://orcid.org/0009-0002-5133-5188
David MelnickFeinberg School of Medicine, Northwestern University, 420 E Superior St, Chicago, IL, 60611, USA.ORCID https://orcid.org/0000-0002-1535-697X
Mozziyar EtemadiFeinberg School of Medicine, Northwestern University, 420 E Superior St, Chicago, IL, 60611, USA.ORCID https://orcid.org/0000-0002-6324-9220
Samantha WinterGoogle Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0000-0002-7300-7903
Thidanun SaensuksopaGoogle Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0009-0009-8966-6194
Alejandra MacielGoogle Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0000-0003-4456-2905
Luca SperoniFeinberg School of Medicine, Northwestern University, 420 E Superior St, Chicago, IL, 60611, USA.ORCID https://orcid.org/0009-0007-9286-1332
Martha SevenichFeinberg School of Medicine, Northwestern University, 420 E Superior St, Chicago, IL, 60611, USA.ORCID https://orcid.org/0009-0001-3209-4860
Arnav AgharwalGoogle Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0009-0005-6078-9407
Rubin ZhangGoogle Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0009-0004-5770-951X
Gavin DugganGoogle Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0000-0002-9869-4447
Shiro KadowakiGoogle Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0009-0004-3144-455X
Atilla P KiralyGoogle Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0000-0002-6613-3581
Jie YangGoogle Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0009-0009-6549-9977
Basil MustafaGoogle Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0000-0001-7305-7890
Yossi MatiasGoogle Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0000-0003-3960-6002
Greg S CorradoGoogle Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0000-0001-8817-0992
Daniel TseGoogle Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0000-0001-5315-8539
Krish EswaranGoogle Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0000-0003-0241-5771
Shravya ShettyGoogle Health, 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA.ORCID https://orcid.org/0000-0003-3783-3172

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMany breast centers are unable to provide immediate results at the time of screening mammography which results in delayed patient care. Implementing artificial intelligence (AI) could identify patients who may have breast cancer and accelerate the time to diagnostic imaging and biopsy diagnosis.

methodsIn this prospective randomized, unblinded, controlled implementation study we enrolled 1000 screening participants between March 2021 and May 2022. The experimental group used an AI system to prioritize a subset of cases for same-visit radiologist evaluation, and same-visit diagnostic workup if necessary. The control group followed the standard of care. The primary operational endpoints were time to additional imaging (T

resultsThe final cohort included 463 experimental and 392 control participants. The one-sided Mann-Whitney U test was employed for analysis of T

conclusionsImplementing AI prioritization can accelerate care timelines for patients requiring additional workup, while maintaining the efficiency of delayed interpretation for most participants. Reducing diagnostic delays could contribute to improved patient adherence, decreased anxiety and addressing disparities in access to timely care.

Indexed as

Artificial IntelligenceBreast NeoplasmsEarly Detection of CancerMammographyTriageAdultAgedFemaleHumansMiddle AgedProspective StudiesArtificial intelligenceDelayed diagnosisScreening mammographyTriage

Identifiers

PMID39881074
PMCPMC11953103

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.