Evidence mapPaperPMID 39882321Full record

ReviewFrontiers in cardiovascular medicine2024

Chinese and western medicine treatment of myocardial fibrosis drugs.

Yuxi Zhu, Fangmei Zhang, Zhongcheng Li, Yu Zhou, Yi Shu, Jian Ruan, Guo Chen

Abstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuxi Zhu *Department of Acupuncture, Bao'an Authentic TCM Therapy Hospital, Shenzheng, China.
Fangmei Zhang *Fever Clinic, The 334 Affiliated Hospital of Nanchang University, Nanchang, China.
Zhongcheng Li *Department of Acupuncture, Bao'an Authentic TCM Therapy Hospital, Shenzheng, China.
Yu Zhou *Department of Acupuncture, Bao'an Authentic TCM Therapy Hospital, Shenzheng, China.
Yi ShuDepartment of Acupuncture, Bao'an Authentic TCM Therapy Hospital, Shenzheng, China.
Jian RuanGraduate School, Jiangxi University of Chinese Medicine, Nanchang, China.
Guo ChenDepartment of Acupuncture, Bao'an Authentic TCM Therapy Hospital, Shenzheng, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial fibrosis (MF) is a common pathological manifestation of many cardiovascular diseases, such as myocardial infarction, myocardial ischemia, and sudden cardiac death. It is characterized by excessive proliferation and activation of fibroblasts, transformation into myofibroblasts, and, eventually, excessive deposition of the extracellular matrix, resulting in heart damage. Currently, modern drugs such as angiotensin-converting enzyme inhibitors, diuretics, and β-blockers can improve myocardial fibrosis in clinical treatment, but their therapeutic effect on this disease is limited, with obvious side effects and high cost. Traditional Chinese medicine (TCM) has the advantages of multiple targets, low cost, and few side effects. Traditional Chinese medicines, such as Salvia miltiorrhiza, Astragalus, and Angelica extracts, and patent Chinese medicines, such as Qiliqiangxin capsules, Shenqi Yiqi dropping pills, and Tongxinluo capsules, can improve myocardial fibrosis. In this review, current Chinese and Western medicine methods for treating myocardial fibrosis are discussed. The signaling pathways and targets of Chinese and Western medicine are involved in the treatment of myocardial fibrosis. This review aimed to provide valuable insights and ideas for both clinical treatment and basic research on myocardial fibrosis.

Indexed as

Chinese medicinedrugsexcessive extracellular matrixmyocardial fibrosisWestern medicine

Identifiers

PMID39882321
PMCPMC11774883

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.