ArticleFrontiers in medicine2024
Global, regional, and national burden inequality of chronic kidney disease, 1990-2021: a systematic analysis for the global burden of disease study 2021.
Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and incidence of hypothyroidism and hyperthyroidism in patients with chronic kidney disease on dialysis: a systematic review and meta-analysis.BMC nephrology · 2026Pooled it
- Association of Chuanhuang Patent Formula with prognosis in patients with acute kidney injury on chronic kidney disease: a retrospective cohort study.Renal failure · 2026Article
- Role of mitochondria-associated ER membranes in lipid metabolism: implications for renal lipotoxicity.Bioscience reports · 2026Review
- Article
- Priorities for Evidence-Based CKD Guidance Using Delphi Methods.Kidney international reports · 2026Article
- Global burden and future trends of type 2 diabetes mellitus-associated chronic kidney disease: analysis of the Global Burden of Disease Study 2021.International journal of clinical pharmacy · 2026Article
- Vaccination of Patients with Chronic Kidney Disease and Cocooning Strategy in a Tertiary Hospital.Vaccines · 2026Article
- Article
- Comparative effectiveness of SGLT-2 inhibitors and GLP-1 receptor agonists on the risk of incident dementia after acute kidney injury: a target-trial emulation.GeroScience · 2026Article
- Burden of chronic kidney disease caused by dietary risks in China from 1990 to 2021: a systematic analysis and comparison with global levels.Journal of clinical biochemistry and nutrition · 2026Article
- Rare variant optimized GWAS with functional validation identifies causal architecture of kidney function in East Asian population.Scientific reports · 2026Article
- Clinical Evaluation of a Disposable Test Strip for Potassium Level Measurement in Patients Treated with Maintenance Hemodialysis.Clinical journal of the American Society of Nephrology : CJASN · 2026Article
- Article
- Unmasking factors affecting sleep pattern disturbances among patients undergoing hemodialysis: A cross-sectional study.PloS one · 2026Article
- Temporal trends and disparities in mortality among US adults with chronic kidney disease and comorbid depression: a population-based analysis, 1999-2023.Frontiers in public health · 2026Article
- Challenges and Lived Realities of Patients With Chronic Kidney Disease in Ghana: A Qualitative Inquiry.Journal of patient experience · 2026Article
- Effects of a structured nutrition education program on dialysis adequacy and clinical outcomes in maintenance hemodialysis patients.Frontiers in nutrition · 2026Article
- Phenotype-specific association of C-reactive protein-to-lymphocyte ratio with incident proteinuric CKD versus isolated eGFR decline: a real-world retrospective cohort study.Frontiers in endocrinology · 2026Article
- From immune dysregulation to renal injury: mechanistic insights and translational opportunities in immune-mediated nephropathies.Frontiers in cell and developmental biology · 2026Review
- Review
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10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chronic kidney disease (CKD) is a significant global health issue, often linked to diabetes, hypertension, and glomerulonephritis. However, aggregated statistics can obscure heterogeneity across subtypes, age, gender, and regions. This study aimed to analyze global CKD trends from 1990 to 2021, focusing on age, gender, socio-demographic index (SDI), and regional variations. Methods: Data were extracted from the Global Burden of Disease (GBD) 2021 database, covering prevalence, incidence, mortality, and disability-adjusted life years (DALYs). These were presented as counts per 100,000 population and age-standardized rates, with uncertainty intervals (UIs) to highlight variability. Joinpoint regression was used to assess trends over the 30-year period. Results: In 2021, global CKD prevalence was 359 million, with 11.13 million new cases, 1.53 million deaths, and 44.45 million DALYs-up 92, 156, 176, and 114% since 1990. While prevalence slightly declined, incidence, mortality, and DALYs increased significantly. CKD burden varied by region and age, with notable gender disparities. Conclusion: The study highlights a dramatic rise in CKD burden linked to population growth and aging, emphasizing the need for targeted treatment and effective global healthcare policies.
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