Evidence map›Paper›PMID 39882860›Full record

ArticleAntimicrobial agents and chemotherapy2025

Assessing the threat of

Nadine Lemaitre, Amélie Dewitte, Faniry Rakotomanimana, David Gooden, Eric Toone, Minoarisoa Rajerison, Pei Zhou, Florent Sebbane

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nadine LemaitreUniv. of Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019-UMR 9017-CIIL-Center for Infection and Immunity of Lille, Lille, France.
Amélie DewitteUniv. of Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019-UMR 9017-CIIL-Center for Infection and Immunity of Lille, Lille, France.
Faniry RakotomanimanaPlague Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
David GoodenDepartment of Chemistry, Duke University, Durham, North Carolina, USA.
Eric TooneDepartment of Chemistry, Duke University, Durham, North Carolina, USA.
Minoarisoa RajerisonPlague Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Pei ZhouDepartment of Biochemistry, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-7823-3416
Florent SebbaneUniv. of Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019-UMR 9017-CIIL-Center for Infection and Immunity of Lille, Lille, France.ORCID 0000-0003-3811-9691

Funding

LpxC inhibitors as a novel class of antibiotics against N. gonorrhoeaeR01AI094475 · NIAID · DUKE UNIVERSITY · PI NICHOLAS, ROBERT A, ZHOU, PEI · 2011 to 2015
$3.7M
Biochemistry and Structure of Lipid A EnzymesR01GM115355 · NIGMS · DUKE UNIVERSITY · PI ZHOU, PEI · 2016 to 2019
$1.2M
Campus France (Agence Française pour la Promotion de l'Enseignement Supérieur, l'Accueil et la Mobilité Internationale)Centre National de la Recherche Scientifique (CNRS)HHS | National Institutes of Health (NIH) R01 GM115355, R01 AI094475Institut National de la Santé et de la Recherche Médicale (Inserm)International Network of Pasteur InstitutesNIAID NIH HHS R01 AI094475NIGMS NIH HHS R01 GM115355Université de Lille (UDL)
6 · The paper itself

Abstract

Self-transmissible IncC plasmids rapidly spread multidrug resistance in many medically important pathogens worldwide. A large plasmid of this type (pIP1202, ~80 Kb) has been isolated in a clinical isolate of

Indexed as

AmidohydrolasesAnti-Bacterial AgentsBacterial ProteinsDrug Resistance, Multiple, BacterialPlaguePlasmidsYersinia pestisAnimalsFemaleMiceMicrobial Sensitivity TestsSiphonapteraVirulenceAmidohydrolasesAnti-Bacterial AgentsBacterial Proteinsdrug targetsFleaLpxCmultidrug resistanceplagueplasmid-mediated resistanceRodentsvirulenceYersinia pestis

Identifiers

PMID39882860
PMCPMC11881579

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.