Evidence map›Paper›PMID 39882906›Full record

ArticlemBio2025

A high-resolution view of the immune and stromal cell response to

Julie A Brothwell, Yuhui Wei, Jia Wang, Tingbo Guo, Chi Zhang, Kate R Fortney, Rory Duplantier, Li Chen, Teresa A Batteiger, Mark H Kaplan and 2 more

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Molecular pathogenesis ofMicrobiology and molecular biology reviews : MMBR · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Julie A Brothwell *Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID 0000-0002-5277-3692
Yuhui Wei *Department of Medical and Molecular Genetics and Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Jia WangDepartment of Computer Science, Indiana University, Bloomington, Indiana, USA.
Tingbo GuoDepartment of Biomedical Engineering, Oregon Health and Science University, Portland, Oregon, USA.
Chi ZhangDepartment of Medical and Molecular Genetics and Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Kate R FortneyDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Rory DuplantierDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Li ChenDepartment of Biostatistics, University of Florida, Gainesville, Florida, USA.
Teresa A BatteigerDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Mark H KaplanDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Stanley M SpinolaDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID 0000-0003-3435-9911
Sha CaoDepartment of Medical and Molecular Genetics and Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID 0000-0002-8645-848X

Funding

Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
Determination of the Interactome between Haemophilus ducreyi and the Human Host.R01AI137116 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI SPINOLA, STANLEY M. · 2020 to 2024
$3.2M
Computational modeling of genetic variations by multi-omics integration todecipher personal genomeR35GM142701 · NIGMS · UNIVERSITY OF FLORIDA · PI CHEN, LI · 2021 to 2025
$1.8M
Advancing computational modeling of disease metabolism by integrating AI and systems biologyR35GM155028 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Sha Cao · 2024 to 2026
$1.2M
HHS | NIH | National Center for Advancing Translational Sciences (NCATS) UL1TR002529HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI137116HHS | NIH | National Institute of General Medical Sciences (NIGMS) R35GM142701HHS | NIH | National Institute of General Medical Sciences (NIGMS) R35GM155028National Science Foundation (NSF) NSF-IIS-2145314NCATS NIH HHS UL1 TR002529NIAID NIH HHS R01 AI137116NIGMS NIH HHS R35 GM142701NIGMS NIH HHS R35 GM155028
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ChancroidHaemophilus ducreyiDendritic CellsFemaleGene Expression ProfilingHealthy VolunteersHumansMacrophagesMaleRNA-SeqSingle-Cell AnalysisSkinTranscriptomeHaemophilus ducreyihuman infectionscRNA-seqspatial transcriptomics

Identifiers

PMID39882906
PMCPMC11898715

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.