Evidence map›Paper›PMID 39883232›Full record

ReviewAdvanced biotechnology2024

Exploring the challenges of RNAi-based strategies for crop protection.

Jian-Hua Zhao, Qing-Yan Liu, Zong-Ming Xie, Hui-Shan Guo

Abstract readReview
In one paragraph

Review in Advanced biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Advances in the Control of Plant Fungal Pathogens.Journal of fungi (Basel, Switzerland) · 2026
    Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Current issues in molecular biology · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Trans-Kingdom sRNA Silencing inPathogens (Basel, Switzerland) · 2025
    Review
  18. All Roads Lead to Rome: Pathways to Engineering Disease Resistance in Plants.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jian-Hua ZhaoState Key Laboratory of Plant Genomics, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Qing-Yan LiuState Key Laboratory of Plant Genomics, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Zong-Ming XieInstitute of Cotton Research, Xinjiang Academy of Agricultural and Reclamation Science, Shihezi, China.
Hui-Shan GuoState Key Laboratory of Plant Genomics, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China. guohs@im.ac.cn.ORCID http://orcid.org/0000-0002-3057-9303

Funding

Science and Technology Bureau of Xinjiang Production and Construction Corps 2022DB014the National Science Foundation of China 32230003
6 · The paper itself

Abstract

RNA silencing (or RNA interference, RNAi) initiated by double-stranded RNAs is a conserved mechanism for regulating gene expression in eukaryotes. RNAi-based crop protection strategies, including host-induced gene silencing (HIGS), spray-induced gene silencing (SIGS) and microbe-induced gene silencing (MIGS), have been successfully used against various pests and pathogens. Here, we highlight the challenges surrounding dsRNA design, large-scale production of dsRNA and dsRNA delivery systems. Addressing these questions will accelerate the lab-to-field transition of RNAi-based strategies. Moreover, based on studies of exogenous dsRNA-induced RNAi inheritance in Caenorhabditis elegans, we speculate that RNAi-based strategies would confer longer-lasting protection for crops against pests or fungal pathogens.

Indexed as

HIGSMIGSRNAiRNAi inheritanceSIGS

Identifiers

PMID39883232
PMCPMC11740845

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.