ArticleBMC oral health2025
Airway morphology, hyoid position, and serum inflammatory markers of obstructive sleep apnea in children treated with modified twin-block appliances.
Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Hyoid bone position with bone-borne or tooth-borne surgically assisted rapid palatal expansion: a retrospective cohort study.Clinical oral investigations · 2025Article
- Assessment of the Effect of Rapid Maxillary Expansion on Nasal Respiratory Function and Obstructive Sleep Apnea Syndrome in Children: A Systematic Review.Journal of clinical medicine · 2025Review
- Impact of Functional Therapy on Skeletal Structures and Airways in Patients with Class II Malocclusion: Comparison of Treatment in Prepubertal and Pubertal Phases.Life (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the effects of modified twin-block appliances (MTBA) on obstructive sleep apnea (OSA) and mandibular retrognathia and the changes in the upper airway, hyoid bone position, and hypoxia-related inflammatory marker levels in children with OSA.
methodsThis study included children with OSA and mandibular retrognathia and those with class I without mandibular retrognathia (n = 35 each). The experimental group comprised children with OSA and mandibular retrognathia managed using MTBA. Postoperative and preoperative polysomnography, lateral cephalometric radiographs, and peripheral blood samples were collected. The control group comprised children with class I without mandibular retrognathia.
resultsFollowing MTBA management, the experimental group exhibited decreased apnea-hypopnea index and increased lowest arterial oxygen saturation level (P < 0.05). Sella- and subspinale-nasion-supramental angles significantly increased and decreased, respectively (P < 0.05). Posterior soft palatal-posterior pharyngeal wall distance, apical palatal-middle pharyngeal wall distance, posterior airway space, epiglottis valley-hypopharyngeal wall distance, hyoid-prevertebral plane distance, and distance from the superior anterior point of the hyoid bone to the inferior anterior point of the third cervical spine significantly increased, whereas distance from the superior anterior point of the hyoid bone to the mandibular plane decreased (P < 0.05).
conclusionsChildren with OSA (n = 35) were managed using MTBA, which relieved the mandibular retrognathia deformity, widened the upper airway space, moved the hyoid bone forward and upward, and improved the sleep monitoring indicators. Thus, MTBA can achieve satisfactory therapeutic effect in children with OSA and mandibular retrognathia with mandibular advancement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.