ArticleJACC. Asia2025
Evaluating Pericoronary Adipose Tissue Attenuation to Predict Cardiovascular Events: A Multicenter Study in East Asians.
Article in JACC. Asia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Systemic inflammation affects the association between pericoronary fat attenuation index and adverse cardiovascular risk in patients with coronary artery disease.The international journal of cardiovascular imaging · 2026Article
- Pericoronary fat attenuation index predicts vulnerable plaque and adverse outcomes in coronary heart disease.Journal of thoracic disease · 2026Article
- Pericoronary adipose tissue radiomics enhances prediction of major adverse cardiovascular events beyond CCTA-derived functional parameters in coronary atherosclerosis.Frontiers in cardiovascular medicine · 2026Article
- Computed tomography-based assessment of pericoronary adipose tissue in cardiovascular diseases: Diagnostic and prognostic implications.World journal of radiology · 2025Review
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Authors and funding
10 authors.
Funding
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Abstract
Background: Pericoronary adipose tissue attenuation (PCATA) is a novel imaging biomarker of pericoronary inflammation associated with coronary artery disease. Several studies have reported the usefulness of PCATA among people of European ethnicity; however, data are lacking concerning those of Asian ethnicity. Objectives: This multicenter study aimed to evaluate the effect of PCATA on prognosis in East Asian patients. Methods: Between August 2011 and December 2016, 2,172 patients underwent clinically indicated coronary computed tomography angiography (CTA) at 4 hospitals in Japan. Among them, 1,270 patients were analyzed. PCATA was evaluated using coronary CTA to measure pericoronary adipose tissue density surrounding the 3 major coronary arteries. The outcomes were composite cardiovascular events, including cardiovascular death and acute coronary syndrome; 33 cardiovascular events observed during a median follow-up of 6.0 years (Q1-Q3: 3.6-8.2 years). Results: Right coronary artery (RCA)-PCATA was significantly higher in patients with cardiovascular events than in those without (-63.7 ± 8.9 HU vs -67.4 ± 9.1 HU, respectively; Conclusions: High RCA-PCATA showed significant association with future cardiovascular events after adjusting conventional risk factors and adverse coronary CTA findings in East Asian patients who underwent clinically indicated coronary CTA.
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