Evidence map›Paper›PMID 39886544›Full record

ArticleFrontiers in nutrition2025

Association between oxidative balance score and glaucoma in the National Health and Nutrition Examination Survey.

Jun Huang, Yulan Zhang, Chao Wu, Yifan Wu, Feiran Wang, Yunxuan Ning, Lu Shi

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jun HuangDepartment of Ophthalmology, The Second Affiliated Hospital, Nanchang University, Nanchang, China.
Yulan ZhangDepartment of Ophthalmology, The Second Affiliated Hospital, Nanchang University, Nanchang, China.
Chao WuDepartment of Ophthalmology, The Second Affiliated Hospital, Nanchang University, Nanchang, China.
Yifan WuDepartment of Ophthalmology, The Second Affiliated Hospital, Nanchang University, Nanchang, China.
Feiran WangDepartment of Ophthalmology, The Second Affiliated Hospital, Nanchang University, Nanchang, China.
Yunxuan NingDepartment of Ophthalmology, The Second Affiliated Hospital, Nanchang University, Nanchang, China.
Lu ShiDepartment of Ophthalmology, The Second Affiliated Hospital, Nanchang University, Nanchang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the association between Oxidative Balance Score (OBS) and glaucoma risk. Methods: Using data from the National Health and Nutrition Examination Survey (2005-2008), we analyzed 2,615 participants aged ≥40 years. OBS was calculated from 15 antioxidant and 5 pro-oxidant components, including dietary nutrients and lifestyle factors. Glaucoma was identified through self-reported diagnosis and retinal imaging. Survey-weighted logistic regression and restricted cubic splines (RCS) were used to assess associations. Results: Higher OBS was associated with lower glaucoma risk (adjusted OR = 0.97, 95% CI: 0.94-1.00). Participants in the highest OBS quartile showed 51% lower odds of glaucoma compared to the lowest quartile (adjusted OR = 0.49, 95% CI: 0.27-0.90). The protective effect was more pronounced among middle-aged adults (40-60 years; OR = 0.90, 95% CI: 0.86-0.95) and males (OR = 0.93, 95% CI: 0.90-0.97). Conclusion: Higher OBS were associated with lower glaucoma prevalence, particularly among middle-aged adults and males, suggesting potential benefits of maintaining oxidative balance in glaucoma prevention.

Indexed as

comprehensive indexglaucomaNational Health and Nutrition Examination Survey (NHANES)oxidative balance scoreoxidative stress

Identifiers

PMID39886544
PMCPMC11774690

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.