Evidence map›Paper›PMID 39887750›Full record

ArticleMedical physics2025

Impact of deep learning reconstructions on image quality and liver lesion detectability in dual-energy CT: An anthropomorphic phantom study.

Aurélie Pauthe, Milan Milliner, Hugo Pasquier, Lucie Campagnolo, Sébastien Mulé, Alain Luciani

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In one paragraph

Article in Medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aurélie PautheInstitut National des Sciences Appliquées, INSA, Toulouse, France.
Milan MillinerService d'Imagerie Médicale, AP-HP, Hôpitaux Universitaires Henri Mondor, Créteil, France.
Hugo PasquierGE Healthcare, Buc, France.
Lucie CampagnoloMedes - IMPS, Institut de Médecine et de Physiologie Spatiales, Toulouse, France.
Sébastien MuléService d'Imagerie Médicale, AP-HP, Hôpitaux Universitaires Henri Mondor, Créteil, France.
Alain LucianiService d'Imagerie Médicale, AP-HP, Hôpitaux Universitaires Henri Mondor, Créteil, France.

Funding

Centre National d'Etudes SpatialesFrench Society of Radiology
6 · The paper itself

Abstract

backgroundDeep learning image reconstruction (DLIR) algorithms allow strong noise reduction while preserving noise texture, which may potentially improve hypervascular focal liver lesions. PURPOSE: To assess the impact of DLIR on image quality (IQ) and detectability of simulated hypervascular hepatocellular carcinoma (HCC) in fast kV-switching dual-energy CT (DECT).

methodsAn anthropomorphic phantom of a standard patient morphology (body mass index of 23 kg m

resultsLesion-to-liver contrast significantly increased with decreasing energy level in both AP and PVP (p ≤ 0.042) but was not affected by reconstruction algorithm (p ≥ 0.57). Overall, noise magnitude increased with decreasing energy levels and was the lowest with ASIRV-100 at all energy levels in both AP and PVP (p ≤ 0.01) and significantly lower with DLIR-M and DLIR-H reconstructions compared to ASIRV-50 and DLIR-L (p < 0.001). For all reconstructions, noise texture within the liver tended to get smoother with decreasing energy; f

conclusionsCompared to the routinely used level of iterative reconstruction, DLIR reduces noise without consequential noise texture modification, and may improve the detectability of hypervascular liver lesions while enabling the use of lower energy virtual monoenergetic images. The optimal energy level and DLIR level may depend on the lesion enhancement.

Indexed as

Deep LearningImage Processing, Computer-AssistedLiverLiver NeoplasmsPhantoms, ImagingTomography, X-Ray ComputedHumansSignal-To-Noise Ratiocomputed tomographydeep learning image reconstructionsdual‐energy CTimage qualityphantom

Identifiers

PMID39887750
PMCPMC11972042

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.