Evidence map›Paper›PMID 39889188›Full record

ReviewMedicine2025

Network pharmacology predicts targets and pathways of herbal components for the treatment of pneumonia: A review.

Dongxin Yang, Cuilian Chen, Qingshang Zhang, Jun Gong

Abstract readReview
In one paragraph

Review in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dongxin YangCentral Laboratory of YunFu People's Hospital, Yunfu, China.ORCID 0009-0005-9243-1653
Cuilian ChenDepartment of Pharmacy, YunFu People's Hospital, Yunfu, China.
Qingshang ZhangDepartment of Pharmacy, YunFu People's Hospital, Yunfu, China.
Jun GongCentral Laboratory of YunFu People's Hospital, Yunfu, China.

Funding

Guangdong Province Bureau of Traditional Chinese Medicine Scientific Research Subject No. 20241398Research Foundation of YunFu People’s Hospital No. A20232001
6 · The paper itself

Abstract

Pneumonia is a respiratory disease with high pathogenicity and mortality. Traditional Chinese medicine (TCM) is a natural therapy that has proven effectiveness and safety. Although TCM has been found to be effective in treating pneumonia, further research is needed to determine the specific mechanism of action. This paper presents a literature search conducted in PubMed, Web of Science, and China National Knowledge Infrastructure (CNKI) databases using the keywords "pneumonia" and "network pharmacology." After screening, we retained the literature related to TCM. The study found that, according to network pharmacology prediction, 4 types of TCMs-natural active compounds, single herb medicine, Chinese patent medicines, and multi-component herbal formulations-were effective in treating pneumonia. TCM components demonstrated a multi-target and multi-pathway approach to treat the disease. The diversity of targets and signaling pathways not only facilitates the investigation of TCM's mechanism of action of TCM in pneumonia treatment but also offers novel insights and perspectives for innovative drug research and development.

Indexed as

Drugs, Chinese HerbalMedicine, Chinese TraditionalNetwork PharmacologyPneumoniaHumansSignal TransductionDrugs, Chinese Herbal

Identifiers

PMID39889188
PMCPMC11789858

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.