Evidence map›Paper›PMID 39890673›Full record

ArticleBreast cancer research and treatment2025

Diet quality and cardiometabolic health in breast cancer survivors: the Pathways Study.

Isaac J Ergas, Richard K Cheng, Janise M Roh, Jacob K Kresovich, Carlos Iribarren, Mai Nguyen-Huynh, Jamal S Rana, Eileen Rillamas-Sun, Cecile A Laurent, Valerie S Lee and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Breast cancer research and treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Isaac J ErgasDivision of Research, Kaiser Permanente Northern California, 4480 Hacienda Drive, Pleasanton, CA, 94558, USA. isaac.j.ergas@kp.org.
Richard K ChengUniversity of Washington School of Medicine, Seattle, WA, USA.
Janise M RohDivision of Research, Kaiser Permanente Northern California, 4480 Hacienda Drive, Pleasanton, CA, 94558, USA.
Jacob K KresovichH. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
Carlos IribarrenDivision of Research, Kaiser Permanente Northern California, 4480 Hacienda Drive, Pleasanton, CA, 94558, USA.
Mai Nguyen-HuynhDivision of Research, Kaiser Permanente Northern California, 4480 Hacienda Drive, Pleasanton, CA, 94558, USA.
Jamal S RanaDivision of Research, Kaiser Permanente Northern California, 4480 Hacienda Drive, Pleasanton, CA, 94558, USA.
Eileen Rillamas-SunDivision of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA.
Cecile A LaurentDivision of Research, Kaiser Permanente Northern California, 4480 Hacienda Drive, Pleasanton, CA, 94558, USA.
Valerie S LeeDivision of Research, Kaiser Permanente Northern California, 4480 Hacienda Drive, Pleasanton, CA, 94558, USA.
Charles P QuesenberryDivision of Research, Kaiser Permanente Northern California, 4480 Hacienda Drive, Pleasanton, CA, 94558, USA.
Ankeet BhattDivision of Research, Kaiser Permanente Northern California, 4480 Hacienda Drive, Pleasanton, CA, 94558, USA.
Song YaoDepartment of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Lawrence H KushiDivision of Research, Kaiser Permanente Northern California, 4480 Hacienda Drive, Pleasanton, CA, 94558, USA.
Heather GreenleeUniversity of Washington School of Medicine, Seattle, WA, USA.
Marilyn L KwanDivision of Research, Kaiser Permanente Northern California, 4480 Hacienda Drive, Pleasanton, CA, 94558, USA.

Funding

Prospective Study of Breast Cancer SurvivorshipR01CA105274 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI KUSHI, LAWRENCE H · 2004 to 2014
$19.9M
Infrastructure for Pathways, a Prospective Study of Breast Cancer SurvivorshipU01CA195565 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI AMBROSONE, CHRISTINE B., KUSHI, LAWRENCE H · 2016 to 2025
$18.8M
Predictors of CVD among breast cancer survivors in an integrated health systemR01CA214057 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI GREENLEE, HEATHER, KWAN, MARILYN L · 2017 to 2020
$2.6M
Developing CVD prediction models for women with early stage breast cancerU01CA214057 · NCI · FRED HUTCHINSON CANCER CENTER · PI Heather Greenlee · 2025 to 2026
$1.5M
NCI NIH HHS R01 CA105274NCI NIH HHS R01CA105274NCI NIH HHS R01 CA214057NCI NIH HHS R01CA214057NCI NIH HHS U01 CA195565NCI NIH HHS U01 CA214057
6 · The paper itself

Abstract

purposeBreast cancer (BC) survivors experience higher rates of cardiometabolic conditions, partly due to treatment. While healthy eating decreases the risk of these conditions in the general population, its association in BC survivors is unclear.

methodsWe included 3415 participants from the Pathways Study, a prospective cohort of women diagnosed with invasive BC between 2005 and 2013 and followed through 2021. Concordance of food intakes from food frequency questionnaires was estimated for five healthy eating patterns at BC diagnosis: Dietary Approaches to Stop Hypertension (DASH), healthy Plant-based Dietary Index (hPDI), 2020 Healthy Eating Index (HEI), American Cancer Society nutrition guidelines (ACS), and the alternate Mediterranean Diet Index (aMED). Incident hypertension, diabetes, and dyslipidemia were identified through electronic health records. Cumulative incidence rates (CIRs) were estimated accounting for the competing risk of death. Covariate-adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated using Fine and Gray regression models, stratified by BC treatment status.

resultsOver an average 11.5 years (range = 0.3-16.3) of follow-up, 554 (16.2%) participants developed hypertension, 362 (10.6%) developed diabetes, and 652 (19.1%) developed dyslipidemia. CIRs for any cardiometabolic condition 15 years after BC diagnosis were 39.2% for women in the highest HEI quartile compared to 49.3% in the lowest. After adjustment, women in the highest HEI quartile had lower risks of any cardiometabolic condition (HR = 0.70, 95% CI 0.54-0.91, P

conclusionHealthier diets at BC diagnosis, particularly those aligned with the HEI, were associated with lower cardiometabolic risks.

Indexed as

Breast NeoplasmsCancer SurvivorsDiet, HealthyHypertensionAdultAgedDiabetes MellitusDyslipidemiasFemaleHumansIncidenceMiddle AgedProspective StudiesBreast cancerDiabetesDiet qualityDyslipidemiaHypertension

Identifiers

PMID39890673
PMCPMC11952977

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.