Evidence map›Paper›PMID 39890694›Full record

ArticleImmunogenetics2025

HCV immunodominant peptide mapping reveals unique HLA-A*02-restricted signatures: insights for CD8

Laura Cardoso Corrêa-Dias, Ágata Lopes-Ribeiro, Geovane Marques-Ferreira, Letícia Gomes-de-Pontes, Thaiza Aline Pereira-Santos, Erik Vinicius de Sousa Reis, Thaís de Fátima Silva Moraes, Olindo Assis Martins-Filho, Edel Figueiredo Barbosa-Stancioli, Flávio Guimarães da Fonseca and 1 more

Erratum issuedAbstract read
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In one paragraph

Article in Immunogenetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Laura Cardoso Corrêa-Dias *Laboratório de Virologia Básica E Aplicada, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Antônio Carlos, 6627 - Pampulha , Belo Horizonte , Minas Gerais, 31270-901, Brazil.
Ágata Lopes-Ribeiro *Laboratório de Virologia Básica E Aplicada, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Antônio Carlos, 6627 - Pampulha , Belo Horizonte , Minas Gerais, 31270-901, Brazil.
Geovane Marques-FerreiraLaboratório de Virologia Básica E Aplicada, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Antônio Carlos, 6627 - Pampulha , Belo Horizonte , Minas Gerais, 31270-901, Brazil.
Letícia Gomes-de-PontesLaboratório de Virologia Básica E Aplicada, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Antônio Carlos, 6627 - Pampulha , Belo Horizonte , Minas Gerais, 31270-901, Brazil.
Thaiza Aline Pereira-SantosLaboratório de Virologia Básica E Aplicada, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Antônio Carlos, 6627 - Pampulha , Belo Horizonte , Minas Gerais, 31270-901, Brazil.
Erik Vinicius de Sousa ReisLaboratório de Virologia Básica E Aplicada, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Antônio Carlos, 6627 - Pampulha , Belo Horizonte , Minas Gerais, 31270-901, Brazil.
Thaís de Fátima Silva MoraesLaboratório de Virologia Básica E Aplicada, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Antônio Carlos, 6627 - Pampulha , Belo Horizonte , Minas Gerais, 31270-901, Brazil.
Olindo Assis Martins-FilhoGrupo Integrado de Pesquisas em Biomarcadores, Instituto René Rachou, Fundação Oswaldo Cruz, Avenida Augusto de Lima, 1,715, Belo Horizonte, Minas Gerais, 30190-009, Brazil.
Edel Figueiredo Barbosa-StancioliLaboratório de Virologia Básica E Aplicada, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Antônio Carlos, 6627 - Pampulha , Belo Horizonte , Minas Gerais, 31270-901, Brazil.
Flávio Guimarães da FonsecaLaboratório de Virologia Básica E Aplicada, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Antônio Carlos, 6627 - Pampulha , Belo Horizonte , Minas Gerais, 31270-901, Brazil.
Jordana Grazziela Coelho-Dos-ReisLaboratório de Virologia Básica E Aplicada, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Antônio Carlos, 6627 - Pampulha , Belo Horizonte , Minas Gerais, 31270-901, Brazil. reisjordana@gmail.com.ORCID http://orcid.org/0000-0002-2360-1875

Funding

FAPEMIG APQ-01499-21
6 · The paper itself

Abstract

Several barriers for the development of an HCV vaccine still exist, including the genetic diversity of the virus, and the shortage of assessable models for in vitro and in vivo assays. Therefore, in this study, HCV epitope mapping was performed for 59 polyprotein sequences from 7 HCV genotypes. Around 2,880 peptides were considered epitopes for CD8

Indexed as

CD8-Positive T-LymphocytesHepacivirusHepatitis CHLA-A2 AntigenImmunodominant EpitopesViral Hepatitis VaccinesAmino Acid SequenceEpitope MappingEpitopes, T-LymphocyteHumansImmunotherapyPeptidesEpitopes, T-LymphocyteHLA-A2 AntigenImmunodominant EpitopesPeptidesViral Hepatitis VaccinesCD8+ T responseCellular immune responseHCVHepatitis CHLA-A*02:01Peptide microarray

Identifiers

PMID39890694

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.