ArticleNature materials2025
Topological linking determines elasticity in limited valence networks.
Article in Nature materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Designing DNA nanostar hydrogels for sequence-specific degradation and antibody release.Soft matter · 2026Article
- Bacteria-responsive DNAgel system for targeted delivery of photothermally enhanced MXene/MoSBioactive materials · 2026Article
- Expression of nano-engineered RNA organelles in bacteria.Nature communications · 2026Article
- Phase-transition-like behaviors of sequence-selective dynamic bonds.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Topologically-crosslinked hydrogels based on γ-cyclodextrins.Communications chemistry · 2025Review
- When stars make loopy networks.Nature materials · 2025Article
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Understanding the relationship between the microscopic structure and topology of a material and its macroscopic properties is a fundamental challenge across a wide range of systems. Here we investigate the viscoelasticity of DNA nanostar hydrogels-a model system for physical networks with limited valence-by coupling rheology measurements, confocal imaging and molecular dynamics simulations. We discover that these networks display a large degree of interpenetration and that loops within the network are topologically linked, forming a percolating network-within-network structure. Below the overlapping concentration, the fraction of branching points and the pore size determine the high-frequency elasticity of these physical gels. At higher concentrations, we discover that this elastic response is dictated by the abundance of topological links between looped motifs in the gel. Our findings highlight the emergence of 'topological elasticity' as a previously overlooked mechanism in generic network-forming liquids and gels and inform the design of topologically controllable material behaviours.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.