Evidence map›Paper›PMID 39892390›Full record

ArticleCell metabolism2025

Sugar-sweetened beverage intake, gut microbiota, circulating metabolites, and diabetes risk in Hispanic Community Health Study/Study of Latinos.

Yanbo Zhang, Kai Luo, Brandilyn A Peters, Yasmin Mossavar-Rahmani, Jee-Young Moon, Yi Wang, Martha L Daviglus, Linda Van Horn, Amanda C McClain, Christina Cordero and 6 more

Abstract read
In one paragraph

Article in Cell metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yanbo ZhangDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Kai LuoDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Brandilyn A PetersDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Yasmin Mossavar-RahmaniDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Jee-Young MoonDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Yi WangDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Martha L DaviglusInstitute for Minority Health Research, University of Illinois Chicago, Chicago, IL, USA.
Linda Van HornDepartment of Preventive Medicine, Northwestern University, Chicago, IL, USA.
Amanda C McClainSchool of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA, USA.
Christina CorderoDepartment of Psychology, University of Miami, Coral Gables, FL, USA.
James S FloydDepartment of Medicine, Department of Epidemiology, University of Washington, Seattle, WA, USA.
Bing YuDepartment of Epidemiology, School of Public Health, The University of Texas Health Science Center, Houston, TX, USA.
Ryan W WalkerDepartment of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Robert D BurkDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA; Departments of Pediatrics, Microbiology & Immunology, and Obstetrics, Gynecology & Women's Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Robert C KaplanDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Qibin QiDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA. Electronic address: qibin.qi@einsteinmed.edu.

Funding

The Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Chris Gennings · 2014 to 2026
$21.3M
Pilot Program CoreP30ES027792 · NIEHS · UNIVERSITY OF CHICAGO · PI Gokhan M. Mutlu, Gail S Prins · 2017 to 2026
$13.6M
DIETARY PATTERNS AND RISK OF CARDIOVASCULAR DISEASER01HL060712 · NHLBI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI HU, FRANK B, QI, QIBIN · 1998 to 2021
$8.0M
New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
Epidemiology of the gut microbiome, prediabetes and diabetes in LatinosR01MD011389 · NIMHD · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI BURK, ROBERT D, KAPLAN, ROBERT C · 2016 to 2020
$4.3M
Ultra-processed Foods, Diet Quality, and Cardiometabolic Health: An Inter-disciplinary Trans-Atlantic Collaborative ProjectR01DK120870 · NIDDK · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Qibin Qi, Qi Sun · 2019 to 2026
$4.2M
Metabolic Signatures Underlying Cardiac Function for Heart Failure in Multi-Ethnic PopulationsR01HL141824 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI YU, BING · 2018 to 2021
$3.1M
Human Gut Microbiome and Incident Diabetes Risk in U.S. PopulationsR01DK126698 · NIDDK · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI QI, QIBIN, SUN, QI · 2021 to 2024
$2.5M
Longitudinal omics-based trajectories of type 2 diabetes subtypes: the T2D Heterogeneity ConsortiumU01DK140761 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Alisa Knodle Manning, Qibin Qi · 2024 to 2026
$2.4M
Metabolomics signatures underlying diet, lifestyle and gut microbiota for diabetesR01DK119268 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI QI, QIBIN · 2019 to 2022
$2.4M
The effects of a high fructose diet on the gut microbiome and metabolic health: A controlled clinical intervention studyR01DK137968 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Ryan Walker · 2024 to 2026
$2.1M
Epidemiology of diet, metabolism and non-alcoholic fatty liver disease in Hispanic/Latino adultsR01DK134672 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI BURK, ROBERT D, KAPLAN, ROBERT C · 2023 to 2025
$2.1M
NHGRI NIH HHS HHSN268201300003CNHLBI NIH HHS HHSN268201300001CNHLBI NIH HHS HHSN268201300003INHLBI NIH HHS HHSN268201300004CNHLBI NIH HHS HHSN268201300005CNHLBI NIH HHS K01 HL150406NHLBI NIH HHS N01 HC065233NHLBI NIH HHS N01 HC065234NHLBI NIH HHS N01 HC065235NHLBI NIH HHS N01 HC065236NHLBI NIH HHS N01 HC065237NHLBI NIH HHS R01 HL060712NHLBI NIH HHS R01 HL141824NIDDK NIH HHS P30 DK111022NIDDK NIH HHS R01 DK119268NIDDK NIH HHS R01 DK120870NIDDK NIH HHS R01 DK126698NIDDK NIH HHS R01 DK134672NIDDK NIH HHS R01 DK137968NIDDK NIH HHS U01 DK140761NIEHS NIH HHS P30 ES023515NIEHS NIH HHS P30 ES027792NIMHD NIH HHS R01 MD011389
6 · The paper itself

Abstract

No population-based studies examined gut microbiota and related metabolites associated with sugar-sweetened beverage (SSB) intake among US adults. In this cohort of US Hispanic/Latino adults, higher SSB intake was associated with nine gut bacterial species, including lower abundances of several short-chain-fatty-acid producers, previously shown to be altered by fructose and glucose in animal studies, and higher abundances of fructose- and glucose-utilizing Clostridium bolteae and Anaerostipes caccae. Fifty-six serum metabolites were correlated with SSB intake and a gut microbiota score based on these SSB-related species in consistent directions. These metabolites were clustered into several modules, including a glycerophospholipid module, two modules comprising branched-chain amino acid (BCAA) and aromatic amino acid (AAA) derivatives from microbial metabolism, etc. Higher glycerophospholipid and BCAA derivative levels and lower AAA derivative levels were associated with higher incident diabetes risk during follow-up. These findings suggest a potential role of gut microbiota in the association between SSB intake and diabetes.

Indexed as

Diabetes MellitusGastrointestinal MicrobiomeHispanic or LatinoSugar-Sweetened BeveragesAdultFemaleHumansMaleMiddle AgedRisk Factorsaromatic amino acidClostridiumdiabetesEubacteriumglucose metabolismglycerophospholipidgut microbiomemetabolitessugar-sweetened beverage

Identifiers

PMID39892390
PMCPMC11885037

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.