Evidence map›Paper›PMID 39892956›Full record

ReviewClinics in perinatology2025

Probiotics and the Risk of Infection.

Noelle Younge, Ravi M Patel

Abstract readReview
In one paragraph

Review in Clinics in perinatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Noelle YoungeDepartment of Pediatrics, Duke University, 2400 Pratt Street, DUMC Box 2739, Durham, NC 27705, USA.
Ravi M PatelDepartment of Pediatrics, Emory University and Children's Healthcare of Atlanta, Arthur M. Blank Hospital, 2220 North Druid Hills Road NE, CL.06323, Atlanta, GA 30329, USA. Electronic address: rmpatel@emory.edu.

Funding

The Microbiome and Metabolism in Postnatal Growth FailureK23DK120960 · NIDDK · DUKE UNIVERSITY · PI YOUNGE, NOELLE ELIZABETH · 2019 to 2022
$874k
Bacterial mediators of postnatal growth in preterm infantsR03DK134684 · NIDDK · DUKE UNIVERSITY · PI YOUNGE, NOELLE ELIZABETH · 2023 to 2024
$237k
NIDDK NIH HHS K23 DK120960NIDDK NIH HHS R03 DK134684
6 · The paper itself

Abstract

Probiotic use has increased in preterm infants and may reduce the risk of necrotizing enterocolitis. Probiotic-associated infection is a concern for infants receiving probiotic supplementation in the neonatal intensive care unit, as highlighted by a recent case and subsequent action by the United States Food and Drug Administration. Based on reports to date, invasive infection is an infrequent but known risk of probiotic supplementation. In this article, we discuss the epidemiology and pathophysiology of invasive infection in preterm infants, review the benefits and risks of probiotic as regulations and available products continue to evolve.

Indexed as

Enterocolitis, NecrotizingProbioticsHumansInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalRisk FactorsUnited StatesDietary supplementNecrotizing enterocolitisNosocomial infectionSepsis

Identifiers

PMID39892956
PMCPMC11789005

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.